In the News

No-biopsy approach can diagnose celiac disease in select adults

IgA anti-tissue transglutaminase levels of at least 10 times the upper limit of normal have a sensitivity of 51% and specificity of 100% for predicting celiac disease in adults referred to secondary care, a meta-analysis found.

Cyclic vomiting syndrome affects 42 per 100,000 Medicaid beneficiaries, study finds

Within 30 days of diagnosis of cyclic vomiting syndrome, only 32% to 35% of adult patients had prescriptions for prophylactic treatment and 47% to 55% for acute treatment, according to an industry-funded study of U.S. claims databases.

Serum ferritin values may improve risk stratification of MASLD patients

Baseline hyperferritinemia occurred in almost one-third of study patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and was associated with higher stages of fibrosis.

MKSAP Quiz: 3-month history of epigastric pain

A 40-year-old woman is evaluated for a 3-month history of epigastric pain, bloating, abdominal fullness, nausea, and diarrhea 30 to 60 minutes after meals that is worse with larger meals. Following a physical exam and other tests, what is the most appropriate treatment?

Spotlight on treatment response in Crohn's disease

Recent studies evaluated early versus late response to biologic therapy, treatment response and infection risk, and endoscopic outcomes.

Case report details serious, recurrent GI bleeding associated with sotatercept

The investigational medication is being evaluated for use in patients with pulmonary arterial hypertension.

Case reports cover gastroenterology topics

De novo Crohn's disease and infectious proctitis due to cytomegalovirus were recently discussed.