Current Issue


New guidance on diagnosis, management of acute hepatic porphyrias

These genetic errors of heme metabolism, although rare, appear to be more common than previously thought, and recent treatment advances have improved the outlook for patients with the diagnoses, according to the American Gastroenterological Association.

Review finds only two efficacious medications to treat gastroparesis

Clebopride ranked first for efficacy, followed by domperidone, and no other drug was superior to placebo for improving symptoms of gastroparesis, according to a recent meta-analysis.

Healthy lifestyle may mitigate genetic risk for inflammatory bowel disease

In a cohort study, U.K. residents with high genetic risk for inflammatory bowel disease who met four or five lifestyle measures developed Crohn's disease or ulcerative colitis at higher-than-average rates, but at about half the rate of those with both genetic risk and an unhealthy lifestyle.

MKSAP Quiz: Persistent epigastric pain despite PPI therapy

This month's quiz asks readers to determine the most appropriate next step in treatment for a 30-year-old patient with progressively worsening epigastric pain that is more severe with eating and has not improved with proton-pump inhibitor (PPI) therapy.

Spotlight on CRC screening and follow-up

Several recent studies focused on screening and follow-up for colorectal cancer (CRC), including one that found differences in decision making between primary care physicians and gastroenterologists on surveillance colonoscopies in older adults.

ACG updates, reaffirms guidelines on evaluation, management of patients with celiac disease

The diagnostic approach to celiac disease in adults using serological and histologic data remains unchanged from the American College of Gastroenterology's (ACG) 2013 clinical guidelines.

Use of warfarin down, DOACs up in commercially insured patients with cirrhosis, nonvalvular afib

While more than half of eligible patients with cirrhosis and concurrent nonvalvular atrial fibrillation did not receive anticoagulation between 2012 and 2019, use of direct oral anticoagulants (DOACs) increased substantially during that time, a recent study found.

EBV monitoring after liver transplant may help reduce incidence of PTLD

A strategy that monitored Epstein-Barr virus (EBV) viral load after liver transplant in adults was associated with decreased incidence of post-transplant lymphoproliferative disease (PTLD), a retrospective Dutch study found.

Case reports published on gastroenterology, hepatology topics

Reports on ibuprofen-induced liver injury, emphysematous gastritis, and cholecystalgia resulting from gallbladder edema were published in the past month.