Current Issue


IV iron appears safe, effective for bleeding-related iron-deficiency anemia in cirrhosis

Patients with cirrhosis who had iron-deficiency anemia after variceal bleeding had greater improvement in clinical outcomes at three months with IV iron versus oral iron therapy, a randomized trial in India found.

GLP-1s associated with lower risk of hepatic decompensation than other diabetes drugs

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes had lower risk of hepatocellular carcinoma than those on insulin or sulfonylureas, and hepatic decompensation risk was reduced compared with five comparison diabetes drug classes, a study found.

Colectomy linked with greater risk of AKI, kidney failure in patients with IBD

Among patients with inflammatory bowel disease (IBD), colectomy was linked with more than doubled risk of acute kidney injury (AKI), indicating that these patients may benefit from close monitoring of kidney biomarkers, according to the authors of a Swedish cohort study.

MKSAP Quiz: 6-month history of dyspepsia

A 25-year-old woman is evaluated for a 6-month history of dyspepsia associated with early satiety, occasional epigastric burning, rare nausea, and postprandial bloating and belching. She has no melena or weight loss. Following a physical exam and other tests, what is the most appropriate management?

Spotlight on colorectal cancer screening intervals

Patients with a complete, negative colonoscopy had reduced risk of colorectal cancer for more than 15 years, one study found, while another found that early-onset colorectal cancer doesn't require more frequent follow-up surveillance than average-onset cases.

Semaglutide effective for patients with HIV and MASLD

More than half of patients with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD) had at least a 30% reduction in intrahepatic triglycerides after 24 weeks on semaglutide, a small uncontrolled study found.

Case of a primary hepatic neuroendocrine tumor

A case report in a patient with tuberous sclerosis may be unique in the literature, the authors said.