There is no evidence that screening for pancreatic cancer or treating screen-detected disease improves disease-specific morbidity or all-cause mortality in average-risk adults with no symptoms, the U.S. Preventive Services Task Force (USPSTF) concluded.
A case-control study found that patients who developed colon cancer, particularly in the proximal colon, were more likely to have taken antibiotics, whereas antibiotic use was not associated with increased risk of rectal cancer.
A retrospective trial showed no increase in new corticosteroid therapy or disease-related hospitalization or surgery among patients who discontinued 5-aminosalycilate (5-ASA) therapy when initiating an anti-tumor necrosis factor (anti-TNF) agent.
Lipophilic statins associated with significantly reduced hepatocellular carcinoma incidence, mortality in hepatitis
Potential benefits of lipophilic statins appeared to be dose- and duration-dependent, with the greatest reduction in hepatocellular carcinoma risk seen with use of a moderate-dose statin for about two years, according to data from a registry of Swedish patients with hepatitis B or C.
Hepatologists from Beth Israel Deaconess Medical Center and University of Michigan Medical Center offered differing opinions on screening and management for nonalcoholic fatty liver disease (NAFLD).
Aspirin before fecal immunochemical testing did not increase sensitivity for detecting advanced colorectal neoplasms
The results of the randomized trial do not support routinely recommending aspirin before fecal immunochemical testing for colorectal cancer screening, according to an ACP Journal Club commentary.
In compensated cirrhosis with portal hypertension, beta-blockers reduced a composite of decompensation or death
The trial results cannot be generalized to all patients with cirrhosis, and future trials should look at whether similar effects could be achieved simply by limiting salt intake, an ACP Journal Club commentary said.