In the News

Trial demonstrates noninferiority of cold snare polyp removal for patients on anticoagulation

Mean procedure time per lesion was significantly shorter with cold snare polypectomy and anticoagulants, whereas the mean hospitalization period was longer in patients receiving hot snare polypectomy and heparin bridging.

Study finds higher proportion of CRC diagnoses in patients under 50 since 2004

Based on the results, study authors suggested expanding colorectal cancer (CRC) screening to patients 45 years of age, but an accompanying editorial expressed concern that the risks could outweigh the benefits in the general population.

Weight loss interventions may improve biomarkers of liver disease in NAFLD

In a meta-analysis of 22 studies in patients with nonalcoholic fatty liver disease (NAFLD), weight loss interventions were associated with improvements in alanine aminotransferase level, liver steatosis, histologic NAFLD activity score, and nonalcoholic steatohepatitis.

MKSAP quiz: Treatment of H. pylori infection

This month's quiz asks readers to determine the most appropriate 14-day treatment regimen for a 65-year-old man with Helicobacter pylori infection that has persisted after eradication therapy.

Spotlight on new guidelines

The American Association for the Study of Liver Diseases, the American Gastroenterological Association, the American College of Gastroenterology, and the U.S. Preventive Services Task Force all released new guidelines this month.

New treatment approved for complicated intra-abdominal infections

The three-drug combination injection contains imipenem-cilastatin, a previously FDA-approved antibiotic, and relebactam, a new beta-lactamase inhibitor.

Financial incentives associated with increased FIT uptake but not increased CRC screening overall

A three-arm trial of incentives for fecal immunochemical testing (FIT) and colorectal cancer screening (CRC) tested mail-only, mail and monetary, and mail and lottery interventions.

Study identifies potential predictors of hospital-onset C. difficile infection

In patients colonized with Clostridioides difficile, risk factors for infection included longer length of stay, exposure to multiple classes of antibiotics, use of opioids, and cirrhosis, whereas use of laxatives was associated with a lower risk.

In CVD, continuing vs interrupting clopidogrel before colonoscopy did not differ for delayed postpolypectomy bleeding

The results of this randomized trial do not support current guidelines, which recommend withholding antiplatelet drugs to reduce risk for postpolypectomy bleeding, an ACP Journal Club commentary said.