For postexposure prophylaxis, the hepatitis A vaccine is now preferred to immune globulin for all adults, including those older than 40 years of age, the Advisory Committee on Immunization Practices (ACIP) said.
In this Swedish case-control study, any previous GI infection and previous bacterial, parasitic, and viral GI infection were associated with higher risk for inflammatory bowel disease (IBD) versus controls.
Patients with ulcerative colitis treated with 5-aminosalicylates who require escalation to anti-tumor necrosis factor-alpha (anti-TNF) therapy may be able to safely discontinue the first drug.
One recent study identified four barriers to follow-up colonoscopy after a positive fecal-based test result, while another found that a delay of six months or more between a positive result and follow-up colonoscopy was associated with an increased risk of colorectal cancer.
The findings may reassure prescribers of dipeptidyl peptidase-4 inhibitors that the drug class does not significantly increase the risk of adverse pancreatic outcomes compared with other second-line therapies, study authors said.