Opioid-induced constipation differs mechanistically from other forms of the disorder, and its medical management deserves dedicated attention, the American Gastroenterological Association (AGA) said.
Gastrointestinal bleeds were less common among at-risk ICU patients who received IV pantoprazole instead of placebo, but rates of clinically important events were similar overall.
Patients with depression had more than double the risk of developing Crohn's disease or ulcerative colitis over a median follow-up of more than six years.
One recent study found a threefold increase in mortality among patients with childhood-onset inflammatory bowel disease (IBD) compared to individuals without the disease, while another found that patients with IBD have a higher risk of certain malignancies compared to the general population.
An accompanying editorial noted that fecal immunochemical testing (FIT) may be less effective in the right colon in part because lesions grow more rapidly and bleed less.
After surgery for stage II or III colorectal cancer, more vs less frequent follow-up did not differ for 5-year mortality
The findings help clarify the ideal process for surveillance of clinical recurrence of colorectal cancer, an ACP Journal Club commentary said.
In primary biliary cholangitis, adding bezafibrate to ursodeoxycholic acid increased complete biochemical response
Bezafibrate is currently unavailable in the U.S., but fenofibrate can be offered off-label in these patients with close monitoring of adverse effects, an ACP Journal Club commentary said.