Search results for "From ACP Diabetes Monthly"
Bariatric surgeries reduced hepatic steatosis in type 2 diabetes at one year
Patients who were randomized to either sleeve gastrectomy or Roux-en-Y gastric bypass showed similar improvements in hepatic steatosis and fibrosis, a randomized trial in Norway found.
https://gastroenterology.acponline.org/archives/2021/12/17/8.htm
17 Dec 2021
DPP-4 inhibitors associated with risk of cholecystitis, meta-analysis finds
Patients with type 2 diabetes who were randomized to receive dipeptidyl peptidase-4 (DPP-4) inhibitors had higher rates of gallbladder disease than those who got placebo or nonincretin drugs, but no difference in risk of cholelithiasis or biliary diseases.
https://gastroenterology.acponline.org/archives/2022/07/22/6.htm
22 Jul 2022
Spotlight on the gut microbiome
A Finnish study found that certain gut bacteria were more common in people who later developed type 2 diabetes, while an Israeli study identified a distinct microbial signature in adults with type 1 diabetes compared with healthy controls.
https://gastroenterology.acponline.org/archives/2022/02/25/8.htm
25 Feb 2022
Severe insulin-resistant diabetes associated with better metabolic surgery outcomes
Patients with severe insulin-resistant diabetes had better outcomes after metabolic surgery than those with mild obesity-related diabetes or severe insulin-deficient diabetes, both in terms of type 2 diabetes remission and renal function, with no additional surgical risk.
https://gastroenterology.acponline.org/archives/2022/03/25/6.htm
25 Mar 2022
GLP-1 receptor agonists linked to increased risk of gallbladder, biliary diseases
A systematic review and meta-analysis of 76 randomized trials found that use of glucagon-like peptide-1 (GLP-1) receptor agonists was associated with increased risk of gallbladder or biliary diseases, especially when used at higher doses, for longer durations, and for weight loss.
https://gastroenterology.acponline.org/archives/2022/04/22/7.htm
22 Apr 2022
Recent-onset diabetes, weight loss associated with increased pancreatic cancer risk
Unintentional weight loss and weight loss in those with a body mass index already in the normal range were particularly associated with risk of pancreatic cancer among patients with recent-onset diabetes, a study found.
https://gastroenterology.acponline.org/archives/2020/09/25/6.htm
25 Sep 2020
Weight loss through gastric bypass or diet improved insulin sensitivity in patients with type 2 diabetes
Results from this small study suggest that reducing adipose tissue volume, by whatever means, will improve blood glucose control in patients with type 2 diabetes, an accompanying editorial noted.
https://gastroenterology.acponline.org/archives/2020/09/25/7.htm
25 Sep 2020
Incretin-based drugs not associated with any increase in risk for pancreatic diseases
The findings may reassure prescribers of dipeptidyl peptidase-4 inhibitors that the drug class does not significantly increase the risk of adverse pancreatic outcomes compared with other second-line therapies, study authors said.
https://gastroenterology.acponline.org/archives/2018/11/27/7.htm
27 Nov 2018
Diabetes remission after bariatric surgery may be more likely in younger patients with shorter disease duration
Long-term results from the Longitudinal Assessment of Bariatric Surgery suggested that diabetes remission is more likely after bariatric surgery performed soon after diagnosis, when diabetes medication burden is low and beta-cell function is preserved, study authors noted.
https://gastroenterology.acponline.org/archives/2020/12/18/8.htm
18 Dec 2020
Roux-en-Y gastric bypass associated with better long-term diabetes outcomes than sleeve gastrectomy
While both procedures were associated with high rates of type 2 diabetes remission, the rate of remission five years after surgery was about 10% higher in patients who had gastric bypass than in those who had sleeve gastrectomy.
https://gastroenterology.acponline.org/archives/2020/03/27/8.htm
27 Mar 2020