https://gastroenterology.acponline.org/archives/2025/06/27/10.htm

From Annals of Internal Medicine: Clinical Cases

Case reports detail syphilitic hepatitis, chronic granulomatous pancreatitis.


Other recent cases covered a rare complication of esophageal stenting and pancytopenia and cirrhosis.

Four recent case reports in Annals of Internal Medicine: Clinical Cases relate to gastroenterology and hepatology.

One case report, published June 17, describes an otherwise healthy young man hospitalized with marked acute liver injury and no evidence of liver failure who, after an extensive work-up, was found to have syphilitic hepatitis. Another case report published on June 17 details a 53-year-old woman with a history of ulcerative esophagitis and esophageal stricture who had undergone esophageal stenting complicated by stent migration and ultimately required esophagectomy with esophagostomy.

On June 3, a case report described a 23-year-old woman with a four-year history of an ambiguous, nonmalignant pancreatic head mass and recurrent nausea/vomiting, right upper quadrant abdominal pain, jaundice, oral feeding intolerance, chronic portal vein thrombosis, and pancytopenia, who was ultimately determined to have chronic granulomatous pancreatitis. Another case report published on June 3 covers a 24-year-old man whose rapid-onset bone marrow failure and cirrhosis were determined to result from an underlying disorder of telomere biology with mutations within the PARN and TERT genes.