Search results for "Highlights"
Review examines drugs, lifestyle treatments for NAFLD
The umbrella review included 27 meta-analyses of randomized controlled trials examining the effectiveness of pharmacological interventions and lifestyle modifications, including diet and exercise, for patients with nonalcoholic fatty liver disease (NAFLD).
https://gastroenterology.acponline.org/archives/2022/05/27/2.htm
27 May 2022
Patient navigation associated with increased care, treatment in hepatitis C
A pre-post study in a safety-net health system found higher odds of linkage to care and direct-acting antiviral treatment in older adults who received patient navigation rather than usual care.
https://gastroenterology.acponline.org/archives/2022/05/27/3.htm
27 May 2022
U.S. antibiotic resistance rates for H. pylori appear high
A systematic review and meta-analysis of resistance patterns of Helicobacter pylori strains found that resistance to metronidazole, levofloxacin, and clarithromycin exceeds 30%.
https://gastroenterology.acponline.org/archives/2022/05/27/1.htm
27 May 2022
Bariatric surgery associated with lower risk of obesity-related cancer
An observational study found significant reductions in a composite outcome of 13 cancers and related mortality in patients with a body mass index of 35 kg/m2 or greater who had bariatric surgery in 2004 to 2017, compared to those who did not undergo surgery for their obesity.
https://gastroenterology.acponline.org/archives/2022/06/24/2.htm
24 Jun 2022
AGA issues guidance on drug treatment for patients with IBS
Two new clinical practice guidelines from the American Gastroenterological Association (AGA) provide recommendations on the use of medications to treat irritable bowel syndrome (IBS) with constipation and IBS with diarrhea.
https://gastroenterology.acponline.org/archives/2022/06/24/1.htm
24 Jun 2022
PPI use in the ICU associated with mortality risk
A systematic review and meta-analysis found that critically ill patients who received proton-pump inhibitors (PPIs) versus any comparator for stress ulcer prophylaxis had a higher risk for death, especially if they were more severely ill at baseline.
https://gastroenterology.acponline.org/archives/2022/06/24/3.htm
24 Jun 2022
Fatty liver disease may not affect mortality risk in elderly patients
In a Dutch cohort study of patients ages 65 years and older, no association was found between hepatic steatosis and death in the overall population or in clinically relevant subgroups.
https://gastroenterology.acponline.org/archives/2022/07/22/3.htm
22 Jul 2022
DPP-4 inhibitors associated with risk of cholecystitis, meta-analysis finds
Patients with type 2 diabetes who were randomized to receive dipeptidyl peptidase-4 (DPP-4) inhibitors had higher rates of gallbladder disease than those who got placebo or nonincretin drugs, but no difference in risk of cholelithiasis or biliary diseases.
https://gastroenterology.acponline.org/archives/2022/07/22/6.htm
22 Jul 2022
HCV medications decreased liver disease among those using injection drugs
A Baltimore-based study found that half of participants with chronic hepatitis C virus (HCV) and a history of injection drug use at baseline were free of the virus by 2019, with associated reductions in their risk of cirrhosis and mortality.
https://gastroenterology.acponline.org/archives/2022/07/22/2.htm
22 Jul 2022
PPIs not associated with mortality risk for most causes, study finds
While patients who took proton-pump inhibitors (PPIs) had significantly higher risks of all-cause mortality and mortality due to cancer, cardiovascular diseases, respiratory diseases, and digestive diseases, lag times of up to six years attenuated these associations so they were no longer statistically significant.
https://gastroenterology.acponline.org/archives/2022/07/22/1.htm
22 Jul 2022