Search results for "Highlights"
Tenofovir alafenamide may safely replace tenofovir disoproxil fumarate in patients with drug-resistant HBV, trial finds
An industry-funded randomized trial found that tenofovir alafenamide could be substituted for tenofovir disoproxil fumarate in patients with multidrug-resistant hepatitis B virus (HBV) for improved bone and renal safety without a loss of efficacy; however, the former drug was associated with greater increases in body weight and cholesterol levels.
https://gastroenterology.acponline.org/archives/2021/05/28/4.htm
28 May 2021
ACG updates clinical guidelines on prevention, diagnosis, treatment of C. difficile infection
While the American College of Gastroenterology (ACG) included new recommendations for using fecal microbiota transplantation in recurrent Clostridioides difficile infection, it recommended against the use of probiotics for both primary and secondary prevention.
https://gastroenterology.acponline.org/archives/2021/05/28/1.htm
28 May 2021
Cost may be common factor in drug nonadherence among patients with chronic liver disease
About 25% of 3,237 respondents with chronic liver disease in the National Health Interview Survey from 2014 through 2018 reported not taking their medications as prescribed due to cost.
https://gastroenterology.acponline.org/archives/2021/06/25/4.htm
25 Jun 2021
Guideline recommends multiple drug classes to treat adults with moderate to severe luminal, fistulizing Crohn's disease
A new clinical practice guideline from the American Gastroenterological Association offered recommendations on which drug classes to use for induction and maintenance of remission, as well as some combination therapies.
https://gastroenterology.acponline.org/archives/2021/06/25/2.htm
25 Jun 2021
Systematic review compares over-the-counter treatments for chronic constipation
Polyethylene glycol and senna had good evidence for their use as first-line laxatives, while moderate evidence supported fiber supplements, fruits, stimulant laxatives, and magnesium-based products.
https://gastroenterology.acponline.org/archives/2021/06/25/3.htm
25 Jun 2021
Patients with IBD who catch COVID-19 have high clot risk, study finds
Infection with SARS-CoV-2 was associated with an eightfold increase in the risk of venous thromboembolism among patients with inflammatory bowel disease (IBD), but the risk was mitigated by chronic anticoagulation, according to a retrospective study.
https://gastroenterology.acponline.org/archives/2021/06/25/1.htm
25 Jun 2021
New best practice advice tackles pain in disorders of gut-brain interaction
An expert review from the American Gastroenterological Association cautioned against using opioids to treat pain from irritable bowel syndrome, functional dyspepsia, or centrally mediated abdominal pain syndrome, among other advice.
https://gastroenterology.acponline.org/archives/2021/07/23/2.htm
23 Jul 2021
Antibody-based multitarget FIT may be more accurate than standard FIT
A multitarget fecal immunochemical test (FIT) could reduce colorectal cancer incidence and death and might be cost-effective, according to a recent validation study.
https://gastroenterology.acponline.org/archives/2021/07/23/3.htm
23 Jul 2021
Spotlight on PPIs and cancer
Recent studies assessed the association between proton-pump inhibitors (PPIs) and cancer, as well as the effects of PPI treatment after a cancer diagnosis.
https://gastroenterology.acponline.org/archives/2021/07/23/5.htm
23 Jul 2021
COVID-19 mRNA vaccines appear effective in patients with cirrhosis
A retrospective cohort study compared outcomes among U.S. veterans with cirrhosis who received at least one dose of an mRNA COVID-19 vaccine with those of a propensity-matched control group of unvaccinated patients at similar risk.
https://gastroenterology.acponline.org/archives/2021/07/23/1.htm
23 Jul 2021