Search results for "Constipation"
First drug approved for fourth-line treatment of advanced GI stromal tumors
A new kinase inhibitor, ripretinib, is now indicated to treat adults with advanced GI stromal tumors who have previously received three or more kinase inhibitor therapies, including imatinib.
https://gastroenterology.acponline.org/archives/2020/05/22/9.htm
22 May 2020
In irritable bowel syndrome, fecal microbiota transplantation improved symptoms at 3 months
While fecal microbiota transplantation was effective in patients with moderate to severe irritable bowel syndrome in a randomized trial, long-term risks of the therapy remain uncertain, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2020/05/22/10.htm
22 May 2020
First-line immunotherapy approved for certain patients with colorectal cancer
Pembrolizumab (Keytruda) for IV injection is now indicated to treat patients with unresectable or metastatic microsatellite instability-high or mismatch repair deficient colorectal cancer.
https://gastroenterology.acponline.org/archives/2020/07/24/8.htm
24 Jul 2020
Use of drugs, nondrug treatments for functional bowel disorders analyzed
One study found that nonpharmacologic interventions are underused in ambulatory care visits for functional bowel disorders, while another found that patients with irritable bowel disease and their insurers have financial incentives to favor differing treatments.
https://gastroenterology.acponline.org/archives/2020/10/23/1.htm
23 Oct 2020
MKSAP Quiz: Treatment of diarrhea and abdominal pain
This month's quiz asks readers to determine the most appropriate treatment for a 35-year-old man with a one-year history of diarrhea and abdominal cramping and bloating.
https://gastroenterology.acponline.org/archives/2020/11/20/4.htm
20 Nov 2020
Semaglutide showed some benefit in patients with NASH, liver fibrosis
Significantly more patients taking the glucagon-like peptide-1 receptor agonist had resolution of their nonalcoholic steatohepatitis (NASH) than those taking placebo, but rates of liver fibrosis improvement were similar between groups, an industry-funded trial found.
https://gastroenterology.acponline.org/archives/2020/11/20/1.htm
20 Nov 2020
First immunotherapy approved for initial treatment of gastric cancer
Nivolumab (Opdivo) is approved in combination with certain types of chemotherapy for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer, or esophageal adenocarcinoma.
https://gastroenterology.acponline.org/archives/2021/04/23/9.htm
23 Apr 2021
Spotlight on functional GI disorders
Research in the past month focused on irritable bowel syndrome (IBS) and functional dyspepsia, finding a worse disease prognosis among patients with both conditions versus IBS alone, as well as sex-based differences and an inverse association between fruit intake and functional dyspepsia symptoms.
https://gastroenterology.acponline.org/archives/2021/04/23/5.htm
23 Apr 2021
Spotlight on COVID-19's impact on gastroenterology
Speakers at Digestive Disease Week shared research on how the COVID-19 pandemic has affected health care utilization, telehealth, and outcomes for patients with GI cancers.
https://gastroenterology.acponline.org/archives/2021/05/28/6.htm
28 May 2021
Systematic review compares over-the-counter treatments for chronic constipation
Polyethylene glycol and senna had good evidence for their use as first-line laxatives, while moderate evidence supported fiber supplements, fruits, stimulant laxatives, and magnesium-based products.
https://gastroenterology.acponline.org/archives/2021/06/25/3.htm
25 Jun 2021