Search results for "Constipation"
In primary care, second-line IBS therapy with amitriptyline vs. placebo reduced symptoms at 6 mo
An ACP Journal Club commentary said the high-quality randomized trial provides pragmatic guidance on amitriptyline dosing in patients with irritable bowel syndrome (IBS), as well as additional support for the drug as an option in primary care after first-line therapies fail.
https://gastroenterology.acponline.org/archives/2024/02/23/7.htm
23 Feb 2024
In symptomatic adults undergoing high-resolution manometry, long-term opioid use was linked to esophageal dysmotility
The results of a recent meta-analysis highlight the need for clinicians to widen their perspective on the risks of opioids to include both upper and lower GI motility disorders, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/12/22/8.htm
22 Dec 2023
Thalidomide reduced bleeding in patients with small-intestinal angiodysplasia
A total of 68.6% of patients who were randomized to 100 mg of thalidomide daily (taken in four doses a day) had a reduction of at least 50% in bleeding episodes in the year after treatment compared to 16% of those on placebo.
https://gastroenterology.acponline.org/archives/2023/12/22/2.htm
22 Dec 2023
MKSAP Quiz: 6-month history of constipation
A 52-year-old man is evaluated for a 6-month history of constipation. He has bowel movements once every 5 days, low back pain after 2 days without a bowel movement, and straining during defecation. He reports no abdominal pain. After a physical exam and lab tests, what is the most appropriate management?
https://gastroenterology.acponline.org/archives/2023/11/17/4.htm
17 Nov 2023
Clinical practice update focuses on belching, bloating, distention
The American Gastroenterological Association offered 15 best practices for physicians caring for patients with these common GI symptoms.
https://gastroenterology.acponline.org/archives/2023/07/28/1.htm
28 Jul 2023
Spotlight on abdominal bloating
Bloating is common throughout the world, is strongly associated with abdominal pain, and may improve with adequate doses of rifaximin, recent studies found.
https://gastroenterology.acponline.org/archives/2023/06/23/5.htm
23 Jun 2023
In persons with constipation or IBS-C, kiwifruit vs. psyllium increased spontaneous bowel movements
Findings of the randomized trial bolster recommendations of diet manipulation and lifestyle modifications for chronic constipation syndromes, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/05/26/7.htm
26 May 2023
Guidance issued on pharmacologic treatment of chronic idiopathic constipation
The joint clinical practice guideline from the American Gastroenterological Association and the American College of Gastroenterology reviewed evidence on fiber, osmotic laxatives, stimulant laxatives, secretagogues, and a serotonin type 4 agonist.
https://gastroenterology.acponline.org/archives/2023/05/26/1.htm
26 May 2023
Improving celiac disease diagnosis
Celiac disease should be a differential diagnosis in patients with several classic clinical presentations, but atypical symptoms, including constipation, can cause doctors to overlook some patients.
https://gastroenterology.acponline.org/archives/2023/02/24/6.htm
24 Feb 2023
MKSAP Quiz: Persistent epigastric pain despite PPI therapy
This month's quiz asks readers to determine the most appropriate next step in treatment for a 30-year-old patient with progressively worsening epigastric pain that is more severe with eating and has not improved with proton-pump inhibitor (PPI) therapy.
https://gastroenterology.acponline.org/archives/2023/01/27/4.htm
27 Jan 2023