Search results for "From ACP Journal Club"
In moderate-to-severe Crohn disease, upadacitinib increased clinical remission at 12 and 52 wk
The benefits of upadacitinib need to be weighed against individual patients' risk profiles, but the drug is an important step forward in treating Crohn disease, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/09/22/9.htm
22 Sep 2023
In symptomatic adults undergoing high-resolution manometry, long-term opioid use was linked to esophageal dysmotility
The results of a recent meta-analysis highlight the need for clinicians to widen their perspective on the risks of opioids to include both upper and lower GI motility disorders, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/12/22/8.htm
22 Dec 2023
In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas
The results of the industry-funded study support the use of the multitarget stool RNA (mt-sRNA) test for screening, but better adherence will be needed, and it is unclear whether the new test offers any advantages over current stool DNA testing, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2024/02/23/6.htm
23 Feb 2024
In primary care, second-line IBS therapy with amitriptyline vs. placebo reduced symptoms at 6 mo
An ACP Journal Club commentary said the high-quality randomized trial provides pragmatic guidance on amitriptyline dosing in patients with irritable bowel syndrome (IBS), as well as additional support for the drug as an option in primary care after first-line therapies fail.
https://gastroenterology.acponline.org/archives/2024/02/23/7.htm
23 Feb 2024