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Q&A: A deeper dive into ACP's new diverticulitis guidelines

Authors discussed the College's first clinical guidelines on diagnosis and management of diverticulitis, which provide recommendations on when to use imaging, antibiotics, colonoscopy, and other interventions.
https://gastroenterology.acponline.org/archives/2022/01/28/1.htm
28 Jan 2022

Review finds upadacitinib most effective for moderate to severe ulcerative colitis remission

The systematic review and meta-analysis of biologic and small-molecule drugs for patients with moderate to severe ulcerative colitis also found that upadacitinib ranked highest for adverse events, whereas vedolizumab had the lowest rate of adverse events and serious adverse events.
https://gastroenterology.acponline.org/archives/2021/12/17/2.htm
17 Dec 2021

Bentonite hemostatic powder noninferior to standard care for GI bleeding

In a single-blind randomized controlled trial, bleeding was controlled within 30 days in 90.1% of adults with acute nonvariceal bleeding on upper GI endoscopy assigned to receive TC-325 versus 81.4% of those assigned to standard treatment.
https://gastroenterology.acponline.org/archives/2021/12/17/3.htm
17 Dec 2021

ACG guideline updates recommendations on diagnosis, management of GERD

Proton-pump inhibitors remain a standard treatment for gastroesophageal reflux disease (GERD) despite increased scrutiny of side effects, although new treatments are emerging, the guideline from the American College of Gastroenterology (ACG) stated.
https://gastroenterology.acponline.org/archives/2021/12/17/1.htm
17 Dec 2021

Patients with mild acute diverticulitis can be safely treated without antibiotics in outpatient setting

Patients who presented to an ED and were randomized to receive only anti-inflammatory and symptomatic treatment had similar rates of hospitalization, return to the ED, and pain control as those who received the usual antibiotic treatment, a Spanish trial found.
https://gastroenterology.acponline.org/archives/2021/11/19/2.htm
19 Nov 2021

AGA releases new guidance on coagulation disorders in patients with cirrhosis

A clinical practice guideline from the American Gastroenterological Association (AGA) suggested against extensive preprocedural testing in patients with stable cirrhosis who are undergoing routine GI procedures, among other recommendations.
https://gastroenterology.acponline.org/archives/2021/11/19/3.htm
19 Nov 2021

Guideline from CRC task force recommends starting screening at ages 45 to 49 years in all average-risk patients

Increasing disease incidence and a favorable harm-benefit ratio are two reasons to expand the age range for colorectal cancer (CRC) screening to younger patients, a task force determined.
https://gastroenterology.acponline.org/archives/2021/11/19/1.htm
19 Nov 2021

Spotlight on COVID-19 vaccines in IBD

Recent research looked at the response to mRNA COVID-19 vaccines among patients with inflammatory bowel disease (IBD), as well as examined COVID-19 vaccine uptake and offered ways to address vaccine hesitancy in this population.
https://gastroenterology.acponline.org/archives/2021/10/22/5.htm
22 Oct 2021

NAFLD progression associated with increased mortality risk

Patients with stage F4 nonalcoholic fatty liver disease (NAFLD) have significantly increased risk for liver-related complications, type 2 diabetes, and all-cause mortality compared to those with earlier stages, an observational prospective study found.
https://gastroenterology.acponline.org/archives/2021/10/22/3.htm
22 Oct 2021

Metabolic syndrome may be linked to pancreatic cancer risk

A nationwide cohort study in Korea found that risk for pancreatic cancer decreased in patients whose metabolic syndrome improved versus persisted over time.
https://gastroenterology.acponline.org/archives/2021/10/22/2.htm
22 Oct 2021

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