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Failure to undergo colonoscopy after positive FIT may double risk for death from colorectal cancer

A retrospective cohort study in Italy compared 10-year cumulative incidence and mortality among patients with a positive result on a fecal immunochemical test (FIT) who completed a diagnostic colonoscopy versus those who did not.
https://gastroenterology.acponline.org/archives/2021/04/23/3.htm
23 Apr 2021

AGA issues guidelines on use of intragastric balloon therapy for patients with obesity

Intragastric balloon therapy can be considered as a weight loss intervention in patients with obesity who have not seen success with conventional therapies, according to the American Gastroenterological Association (AGA).
https://gastroenterology.acponline.org/archives/2021/04/23/2.htm
23 Apr 2021

Fatty liver disease associated with increased risk of COVID-19 infection, hospitalization

However, patients who were obese but did not have fatty liver disease were not at increased risk of hospitalization for COVID-19, according to a study of healthy people in a U.K. database who underwent MRI assessment of liver fat markers.
https://gastroenterology.acponline.org/archives/2021/04/23/1.htm
23 Apr 2021

GI symptoms associated with better outcomes from COVID-19, new two-part study finds

SARS-CoV-2 was commonly present in the gastrointestinal tract but didn't cause inflammation there, according to a recent analysis of intestinal biopsy tissues from patients with COVID-19.
https://gastroenterology.acponline.org/archives/2021/03/26/2.htm
26 Mar 2021

Use of PPIs may be associated with C. difficile infections

A Danish nationwide cohort study found that ongoing exposure to proton-pump inhibitors (PPIs) was associated with moderately increased community-associated Clostridioides difficile infection risk during treatment and for up to one year afterward.
https://gastroenterology.acponline.org/archives/2021/03/26/3.htm
26 Mar 2021

ACG lowers suggested age for colorectal cancer screening in updated guidelines

The American College of Gastroenterology (ACG) continues to recommend colorectal cancer screening in average-risk adults ages 50 to 75 years but now also suggests it in those ages 45 to 49 years.
https://gastroenterology.acponline.org/archives/2021/03/26/1.htm
26 Mar 2021

Half of overweight, obese adults may have fatty liver disease

The global prevalence of metabolic dysfunction-associated fatty liver disease, a newly proposed term for nonalcoholic fatty liver disease, is “astonishingly high,” the authors of a recent meta-analysis found.
https://gastroenterology.acponline.org/archives/2021/02/26/3.htm
26 Feb 2021

Amoxicillin-clavulanate appears safe, effective for diverticulitis in outpatients

A retrospective cohort study compared amoxicillin-clavulanate with metronidazole-fluoroquinolone and found no differences in outcomes including risks for inpatient admission or surgery, while Clostridioides difficile risk appeared higher in older patients on the latter regimen.
https://gastroenterology.acponline.org/archives/2021/02/26/2.htm
26 Feb 2021

Effects of gastric acid suppression drugs on COVID-19 outcomes still unclear

A meta-analysis didn't find an association between famotidine use and severe disease or death from COVID-19, and the association of these outcomes with proton-pump inhibitors varied by study type.
https://gastroenterology.acponline.org/archives/2021/02/26/1.htm
26 Feb 2021

Prevalence of liver fibrosis in diabetes suggests need for earlier intervention, study finds

The prevalence of any suspected liver fibrosis in patients with diabetes was 21% in a recent study, leading the authors to call for more aggressive screening in patients with obesity and diabetes.
https://gastroenterology.acponline.org/archives/2021/01/22/3.htm
22 Jan 2021

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