Search results for "Cirrhosis"
Spotlight on cirrhosis
Patients with cirrhosis were the focus of several recent studies, which reviewed the evidence behind nutritional assessment, calculated the cost-effectiveness of hepatocellular carcinoma screening, and estimated the prevalence of nonalcoholic steatohepatitis-associated cirrhosis.
https://gastroenterology.acponline.org/archives/2017/02/24/5.htm
24 Feb 2017
Pioglitazone associated with improved advanced fibrosis in patients with NASH
A recent meta-analysis looked at randomized clinical trials that examined the effect of thiazolidinediones on liver histology in patients with nonalcoholic steatohepatitis (NASH).
https://gastroenterology.acponline.org/archives/2017/03/24/1.htm
24 Mar 2017
High HCV cure rate seen with FDA-approved direct-acting antiviral regimens
Six of the direct-acting antiviral (DAA) regimens yielded sustained virologic response rates above 95% in patients who had hepatitis C virus (HCV) genotype 1 without cirrhosis, including those with HIV co-infection.
https://gastroenterology.acponline.org/archives/2017/03/24/7.htm
24 Mar 2017
MKSAP quiz: New-onset ascites with lower-extremity edema
What is the most likely cause of this 68-year-old man's ascites?
https://gastroenterology.acponline.org/archives/2017/03/24/5.htm
24 Mar 2017
8 weeks of ledipasvir/sofosbuvir may be effective for genotype 1 hepatitis C
The therapy should be considered in patients with genotype 1 infection who are treatment-naive, do not have cirrhosis, and have a pretreatment viral load below 6,000,000 IU/mL, a study found.
https://gastroenterology.acponline.org/archives/2017/03/24/2.htm
24 Mar 2017
Risk of liver-related death linked to increased fibrosis stage in NAFLD
The systematic review and meta-analysis included five studies of 1,495 adult patients with nonalcoholic fatty liver disease (NAFLD), encompassing 17,452 patient-years of follow-up.
https://gastroenterology.acponline.org/archives/2017/04/28/2.htm
28 Apr 2017
Anticoagulants safe, effective in cirrhosis with portal vein thrombosis, review finds
Researchers analyzed eight studies with 353 patients to assess the effect of low-molecular-weight heparin or warfarin on recanalization, thrombosis progression, and bleeding.
https://gastroenterology.acponline.org/archives/2017/05/26/3.htm
26 May 2017
Spotlight on statin therapy
Studies published in May found a potential benefit of statin therapy for three different conditions.
https://gastroenterology.acponline.org/archives/2017/05/26/5.htm
26 May 2017
Cirrhosis associated with increased risk of stroke, study finds
Researchers performed a retrospective cohort study using a random 5% sample of more than 1.6 million inpatient and outpatient Medicare claims from Jan. 1, 2008, through Dec. 31, 2014.
https://gastroenterology.acponline.org/archives/2017/06/23/2.htm
23 Jun 2017
HCV treatment appeared successful for patients who hadn't responded to previous direct-acting antivirals, industry-funded study finds
The study included two phase 3 trials: POLARIS-1, in which patients with chronic hepatitis C virus (HCV) had previously taken a regimen containing an NS5A inhibitor, and POLARIS-4, in which patients had previously received a direct-acting antiviral agent regimen that did not include an NS5A inhibitor.
https://gastroenterology.acponline.org/archives/2017/06/23/3.htm
23 Jun 2017