Search results for "Cirrhosis"
Practice guidance addresses vascular liver disorders, portal vein thrombosis, procedural bleeding
Among other statements, the American Association for the Study of Liver Diseases said that modifiable risk factors for bleeding, such as use of antithrombotic drugs, should be identified and corrected before procedures in patients with cirrhosis.
https://gastroenterology.acponline.org/archives/2020/12/18/2.htm
18 Dec 2020
Spotlight on alcohol-related liver disease
Recent research identified risk factors that predict the severity of alcohol-related liver disease, distinct patterns of alcohol use that may affect survival after liver transplantation for alcoholic hepatitis, potential effects on the microbiome, and more.
https://gastroenterology.acponline.org/archives/2020/12/18/5.htm
18 Dec 2020
Prevalence of liver fibrosis in diabetes suggests need for earlier intervention, study finds
The prevalence of any suspected liver fibrosis in patients with diabetes was 21% in a recent study, leading the authors to call for more aggressive screening in patients with obesity and diabetes.
https://gastroenterology.acponline.org/archives/2021/01/22/3.htm
22 Jan 2021
Antibiotic may prevent hepatic encephalopathy after TIPS in patients with cirrhosis
A French trial found that 34% of patients who received rifaximin before and after placement of a transjugular intrahepatic portosystemic shunt (TIPS) had hepatic encephalopathy versus 53% of those who received placebo, with no differences in adverse events or transplant-free survival.
https://gastroenterology.acponline.org/archives/2021/02/26/7.htm
26 Feb 2021
MKSAP Quiz: Management of HBV infection
This month's quiz asks readers to determine the most appropriate next step in management of a 29-year-old woman with hepatitis B virus (HBV) infection and normal liver enzyme levels.
https://gastroenterology.acponline.org/archives/2021/04/23/4.htm
23 Apr 2021
MKSAP Quiz: Dyspnea in a patient with liver disease
A 48-year-old woman with cirrhosis due to primary biliary cholangitis reports shortness of breath of six weeks' duration. Her oxygen saturation is 98% while supine, but it drops to 92% with standing. What is the most appropriate diagnostic test?
https://gastroenterology.acponline.org/archives/2021/05/28/5.htm
28 May 2021
FDA restricts use of liver disease drug in certain patients
The agency added new warnings to the prescribing information for obeticholic acid, including a contraindication in patients with primary biliary cholangitis and advanced cirrhosis.
https://gastroenterology.acponline.org/archives/2021/06/25/7.htm
25 Jun 2021
COVID-19 mRNA vaccines appear effective in patients with cirrhosis
A retrospective cohort study compared outcomes among U.S. veterans with cirrhosis who received at least one dose of an mRNA COVID-19 vaccine with those of a propensity-matched control group of unvaccinated patients at similar risk.
https://gastroenterology.acponline.org/archives/2021/07/23/1.htm
23 Jul 2021
In patients having transjugular intrahepatic portosystemic shunt, rifaximin prevented overt hepatic encephalopathy
Results from a French trial provide the best available evidence to justify using the expensive antibiotic in patients with hepatic encephalopathy associated with transjugular intrahepatic portosystemic shunt, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2021/07/23/7.htm
23 Jul 2021
In decompensated cirrhosis, targeted albumin infusions did not improve an in-hospital composite outcome at 15 days
The results of this randomized trial should not discourage clinicians from using albumin for recognized indications, but they do not support targeting an arbitrary serum albumin level, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2021/08/27/7.htm
27 Aug 2021