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Patients may not always want to stop low-value colorectal cancer screening

Veterans at one health system were asked to rate the reasonableness of using age and risk calculators in decisions about screening cessation.
https://gastroenterology.acponline.org/archives/2018/12/28/1.htm
28 Dec 2018

AGA issues guideline on opioid-induced constipation

Opioid-induced constipation differs mechanistically from other forms of the disorder, and its medical management deserves dedicated attention, the American Gastroenterological Association (AGA) said.
https://gastroenterology.acponline.org/archives/2018/10/26/1.htm
26 Oct 2018

Insufficient evidence to support gluten-free diet for IBS, meta-analysis finds

Included trials evaluated an exclusion diet versus an alternative or usual diet and assessed improvement in either global symptoms of irritable bowel syndrome (IBS) or abdominal pain.
https://gastroenterology.acponline.org/archives/2018/08/24/1.htm
24 Aug 2018

8 weeks of ledipasvir/sofosbuvir may be effective for genotype 1 hepatitis C

The therapy should be considered in patients with genotype 1 infection who are treatment-naive, do not have cirrhosis, and have a pretreatment viral load below 6,000,000 IU/mL, a study found.
https://gastroenterology.acponline.org/archives/2017/03/24/2.htm
24 Mar 2017

Endoscopic eradication therapy plus reflux control associated with decreased Barrett's recurrence rates

Standard reflux management protocol involved initial consultation that emphasized reflux control and proton-pump inhibitor (PPI) adherence, initiation or continuation of PPI therapy as described, medication reconciliation and assessment or remediation of PPI adherence at each study visit, and on-treatment reflux testing.
https://gastroenterology.acponline.org/archives/2017/02/24/2.htm
24 Feb 2017

Anticoagulants safe, effective in cirrhosis with portal vein thrombosis, review finds

Researchers analyzed eight studies with 353 patients to assess the effect of low-molecular-weight heparin or warfarin on recanalization, thrombosis progression, and bleeding.
https://gastroenterology.acponline.org/archives/2017/05/26/3.htm
26 May 2017

GI safety profile varies among direct oral anticoagulants

Three propensity-matched cohorts of patients with nonvalvular atrial fibrillation who had incident exposure to dabigatran, rivaroxaban, or apixaban were compared.
https://gastroenterology.acponline.org/archives/2017/01/27/2.htm
27 Jan 2017

Probiotics reduce C. difficile in hospitalized patients on antibiotics, review finds

In 19 randomized controlled trials of 6,261 hospitalized patients on antibiotics, the incidence of C. difficile was 1.6% among patients taking probiotics compared to 3.9% in controls.
https://gastroenterology.acponline.org/archives/2017/02/24/3.htm
24 Feb 2017

Guideline released on treatment of Helicobacter pylori infection

Clarithromycin triple therapy should be used for first-line treatment of Helicobacter pylori infection only in patients with no history of macrolide exposure who live in areas where H. pylori resistance to clarithromycin is known to be low, among other recommendations.
https://gastroenterology.acponline.org/archives/2017/01/27/3.htm
27 Jan 2017

GI bleeding less common in U.S. veterans on NOACs than those on warfarin

Significant bleeding occurred in 2.5% of the patients on warfarin and 0.6% of the patients on non-vitamin K antagonist oral anticoagulants (NOACs).
https://gastroenterology.acponline.org/archives/2017/03/24/3.htm
24 Mar 2017

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