Search results for "Highlights"
Adding baclofen may improve GERD symptoms, but long-term use may increase side effects
Add-on therapy with baclofen reduced reflux symptoms among patients with refractory gastroesophageal reflux disease (GERD) but prolonged use led to an increased incidence of side effects and failed to effectively reduce acid reflux occurrence, a review found.
https://gastroenterology.acponline.org/archives/2024/06/28/3.htm
28 Jun 2024
GLP-1s associated with lower risk of hepatic decompensation than other diabetes drugs
Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes had lower risk of hepatocellular carcinoma than those on insulin or sulfonylureas, and hepatic decompensation risk was reduced compared with five comparison diabetes drug classes, a study found.
https://gastroenterology.acponline.org/archives/2024/05/24/2.htm
24 May 2024
Colectomy linked with greater risk of AKI, kidney failure in patients with IBD
Among patients with inflammatory bowel disease (IBD), colectomy was linked with more than doubled risk of acute kidney injury (AKI), indicating that these patients may benefit from close monitoring of kidney biomarkers, according to the authors of a Swedish cohort study.
https://gastroenterology.acponline.org/archives/2024/05/24/3.htm
24 May 2024
Gastro experts offer best practice advice on iron to treat anemia
The American Gastroenterological Association issued a clinical practice update on management of iron-deficiency anemia, including when to use oral versus IV iron and how to handle anemia related to GI conditions.
https://gastroenterology.acponline.org/archives/2024/06/28/1.htm
28 Jun 2024
Higher MAP linked with AKI reversal among hospitalized patients
A 5 mm Hg increase in mean arterial pressure (MAP) was linked with a small but significant increase in the likelihood of reversal of acute kidney injury (AKI), according to a retrospective study of patients hospitalized with decompensated cirrhosis.
https://gastroenterology.acponline.org/archives/2024/04/26/2.htm
26 Apr 2024
IV iron appears safe, effective for bleeding-related iron-deficiency anemia in cirrhosis
Patients with cirrhosis who had iron-deficiency anemia after variceal bleeding had greater improvement in clinical outcomes at three months with IV iron versus oral iron therapy, a randomized trial in India found.
https://gastroenterology.acponline.org/archives/2024/05/24/1.htm
24 May 2024
GLP-1 receptor agonists could modestly delay gastric emptying during periprocedural fasting, study suggests
A systematic review and meta-analysis found that glucagon-like peptide-1 (GLP-1) receptor agonists were associated with a delay of approximately 36 minutes in gastric emptying on scintigraphy compared to placebo.
https://gastroenterology.acponline.org/archives/2024/04/26/3.htm
26 Apr 2024
Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation
Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024
Restricting PPI prescription refills reduced use without noticeable clinical effects
Restrictions on proton-pump inhibitor (PPI) refills for patients without a documented long-term indication were associated with a rapid and sustained 7.3% absolute reduction in such prescriptions—a relative decline of nearly 30%, a Veterans Affairs study found.
https://gastroenterology.acponline.org/archives/2024/04/26/1.htm
26 Apr 2024
Review finds antibiotics associated with heightened risk of inflammatory bowel disease
There was a positive, nonlinear dose-response association between the number of antibiotic prescriptions patients received and their inflammatory bowel disease risk, according to a systematic review.
https://gastroenterology.acponline.org/archives/2024/03/22/2.htm
22 Mar 2024