Search results for "Highlights"
Noninvasive methods show promise for CRC screening
A DNA blood-based test had approximately 83% sensitivity for colorectal cancer (CRC) and 13% sensitivity for advanced precancerous lesions in one industry-funded study, while a next-generation multitarget stool DNA test showed higher sensitivity but lower specificity for CRC and advanced precancerous lesions than fecal immunochemical testing in another.
https://gastroenterology.acponline.org/archives/2024/03/22/1.htm
22 Mar 2024
Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation
Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024
Review finds antibiotics associated with heightened risk of inflammatory bowel disease
There was a positive, nonlinear dose-response association between the number of antibiotic prescriptions patients received and their inflammatory bowel disease risk, according to a systematic review.
https://gastroenterology.acponline.org/archives/2024/03/22/2.htm
22 Mar 2024
Restricting PPI prescription refills reduced use without noticeable clinical effects
Restrictions on proton-pump inhibitor (PPI) refills for patients without a documented long-term indication were associated with a rapid and sustained 7.3% absolute reduction in such prescriptions—a relative decline of nearly 30%, a Veterans Affairs study found.
https://gastroenterology.acponline.org/archives/2024/04/26/1.htm
26 Apr 2024
Score validated to assess patients with laryngeal symptoms for risk of GERD
In a study of 856 adults with chronic laryngeal symptoms, researchers created and validated a risk score, called COuGH RefluX, that is 79% sensitive and 81% specific for identifying gastroesophageal reflux disease (GERD).
https://gastroenterology.acponline.org/archives/2024/02/23/2.htm
23 Feb 2024
Spotlight on cholesterol and the liver
Very low low-density lipoprotein cholesterol levels are associated with increased risk of liver complications in the general population, a European study found, while a study of Chinese patients with primary biliary cholangitis showed that high total cholesterol levels predicted liver disease.
https://gastroenterology.acponline.org/archives/2024/02/23/5.htm
23 Feb 2024
Undiagnosed liver disease frequently found among patients with cognitive impairment
Among 177,422 veterans with dementia and no prior cirrhosis diagnosis, 10.3% had a Fibrosis-4 score suggestive of advanced fibrosis and 5.3% had a score suggestive of cirrhosis.
https://gastroenterology.acponline.org/archives/2024/02/23/3.htm
23 Feb 2024
Serum ferritin values may improve risk stratification of MASLD patients
Baseline hyperferritinemia occurred in almost one-third of study patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and was associated with higher stages of fibrosis.
https://gastroenterology.acponline.org/archives/2024/01/26/3.htm
26 Jan 2024
Cyclic vomiting syndrome affects 42 per 100,000 Medicaid beneficiaries, study finds
Within 30 days of diagnosis of cyclic vomiting syndrome, only 32% to 35% of adult patients had prescriptions for prophylactic treatment and 47% to 55% for acute treatment, according to an industry-funded study of U.S. claims databases.
https://gastroenterology.acponline.org/archives/2024/01/26/2.htm
26 Jan 2024
Spotlight on treatment response in Crohn's disease
Recent studies evaluated early versus late response to biologic therapy, treatment response and infection risk, and endoscopic outcomes.
https://gastroenterology.acponline.org/archives/2024/01/26/5.htm
26 Jan 2024