ACP Gastroenterology Monthly

AGA releases best practice advice on cirrhosis

The guidance from the American Gastroenterological Association (AGA) covered management of ascites, hepatic hydrothorax, volume overload, and hyponatremia in and out of the hospital.

Vonoprazan improved nocturnal reflux symptoms in nonerosive disease, industry trial found

Vonoprazan had a rapid effect on nighttime heartburn symptoms that was sustained through 24 weeks, a phase 3 placebo-controlled trial found.

Elevated uric acid linked with increased risk of MAFLD, review shows

Patients with the highest serum uric acid levels were 1.9 times more likely to develop metabolic dysfunction-associated fatty liver disease (MAFLD) than those with the lowest levels, a meta-analysis of 61 studies with more than two million participants found.

Test yourself

MKSAP Quiz: 1-day history of abdominal pain

A 59-year-old woman is evaluated for a 1-day history of persistent left-lower-quadrant abdominal pain and constipation. She describes the pain as cramping discomfort and states that she has never experienced similar symptoms in the past. Following a physical exam, lab studies, and a CT, what is the most appropriate management?

Keeping tabs

Spotlight on cancer trends

Mortality from gastric cancer in the U.S. was lower in 2022 than 1999, one study showed, while another provided the first evidence of a drop in incidence of hepatocellular carcinoma among those older than age 65 years beginning in 2019.

From Annals of Internal Medicine: Clinical Cases

Case reports cover rare gastroenterology, hepatology topics

One recent case discusses dysphagia lusoria, and another describes acute liver failure secondary to herpes simplex virus hepatitis.

From ACP Journal Club

In primary CDI, fecal microbiota transplantation was noninferior to vancomycin for clinical cure at 14 d without recurrence at 60 d

Although fecal microbiota transplantation is a potentially attractive treatment for primary Clostridioides difficile infection (CDI), it's unlikely to become the standard of care in the near future because of both clinical questions and logistical issues, an ACP Journal Club commentary said.