In the News

Guidance offered for managing colorectal dysplasia in patients with IBD

Among other best practice advice from the American Gastroenterological Association, precancerous colorectal lesions in patients with inflammatory bowel disease (IBD) should be described as polypoid, nonpolypoid, or invisible using a modified Paris Classification.

Biopsy-proven NAFLD associated with higher rates of MACE

Patients in a Swedish study whose nonalcoholic fatty liver disease (NAFLD) was confirmed on biopsy were more likely to experience incident major adverse cardiovascular events (MACE).

Urinary biomarker may help predict cirrhosis outcomes, study finds

Levels of urine liver fatty acid-binding protein could be used together with Model for End-stage Liver Disease scoring to improve predictions of liver failure or death, according to an analysis of patients hospitalized for decompensated cirrhosis.

MKSAP Quiz: Evaluation of small-bowel bleeding

This month's quiz asks readers to determine the most appropriate diagnostic test to perform next in a 55-year-old patient with iron deficiency anemia after an upper endoscopy and a colonoscopy did not find the source of suspected small-bowel bleeding.

Spotlight on COVID-19 and GI cancers

Recent international studies found that the COVID-19 pandemic may be associated with fewer new diagnoses of gastric cancer and colorectal cancer (CRC), as well as increased tumor burden in patients with newly diagnosed metastatic CRC.

Be on alert for CRC in younger patients

A story in the September ACP Internist explained why medical groups are coming to consensus about expanded screening guidelines for colorectal cancer (CRC) that lower the age to begin screening.

Managing patients with abnormal liver test results in primary care

An In the Clinic article provided an overview of caring for patients with abnormal liver test results in primary care settings, including evaluation, management, practice improvement, and patient education.

In adults with obesity, metabolic–bariatric surgery vs. usual care is associated with lower all-cause mortality

A recent meta-analysis leaves little question that metabolic surgery is lifesaving compared with usual care, yet only 1% of eligible patients are treated with surgery, an ACP Journal Club commentary noted.

FDA requires updated boxed warnings on heart-related events, other risks for certain Janus kinase inhibitors

The agency is requiring revisions to the boxed warning for the arthritis and ulcerative colitis medicine tofacitinib, as well as two other Janus kinase inhibitors, to include information about the risks of serious heart-related events, cancer, blood clots, and death.