The American Gastroenterological Association recommended that probiotics be used to treat patients with Clostridioides difficile infection, Crohn's disease, ulcerative colitis, or irritable bowel syndrome only in the context of a clinical trial.
Patients with inflammatory bowel disease were diagnosed with dementia an average of seven years earlier than matched controls in a Taiwanese study.
Rates of clinical remission and clinical response were 32.0% and 42.7%, respectively, in Crohn's disease patients receiving therapy with both corticosteroids and anti-tumor necrosis factor (TNF) agents and 35.5% and 46.8% in those receiving only anti-TNF agents, a systematic review and meta-analysis found.
A 48-year-old man with primary sclerosing cholangitis and ulcerative colitis presents to the hospital with fever, rigors, right-upper-quadrant pain, and leukocytosis. Blood cultures are pending. After giving IV saline and IV piperacillin-tazobactam, which next test is most appropriate?
Patients who received a high-quality colonoscopy had profound and stable reductions in colorectal cancer incidence and mortality throughout study follow-up, compared to the general population and to those who received low-quality colonoscopy, a Polish study found.
H. pylori treatment reduced risk for gastric cancer in patients with a family history of gastric cancer
While results of the trial support a test-and-treat screening approach for Helicobacter pylori in patients with a first-degree relative with gastric cancer, more research is needed before considering universal screening in this population, an ACP Journal Club commentary noted.