In the News

Early-onset colorectal cancer increases sharply between ages 49 and 50, study finds

According to U.S. registry data, incidence of colorectal cancer increased 46.1% from age 49 years to age 50 years, from 34.9 to 51.0 per 100,000 population.

Recommendations updated on surveillance after colonoscopy and polypectomy

New evidence supports closer follow-up for some patients and less surveillance for others, according to a task force of the American College of Gastroenterology, American Gastroenterological Association, and American Society for Gastrointestinal Endoscopy.

Internists may overestimate risks of PPIs, survey suggests

A survey of internists showed that 79% inappropriately recommended stopping proton-pump inhibitors (PPIs) in a prevention scenario focusing on high-risk upper gastrointestinal bleeding.

MKSAP Quiz: 3-month history of dysphagia, regurgitation

A 52-year-old man is evaluated for dysphagia of 3 months' duration. He reports regurgitating undigested food soon after eating solid food, occasional coughing and choking after swallowing, and chronic halitosis. What is the most appropriate diagnostic test to perform next?

Spotlight on dietary interventions

The International Organization for the Study of Inflammatory Bowel Disease recently released new dietary guidance, and two studies found that adherence to a Mediterranean diet may beneficially alter the gut microbiome in older adults and those with cardiometabolic risk factors.

FDA requests withdrawal of weight-loss drug from U.S. market

The manufacturer of lorcaserin will voluntarily withdraw the drug because a safety clinical trial showed that the drug was associated with an increased occurrence of cancer compared to placebo.

FDA strengthens warning that schizophrenia drug can lead to life-threatening constipation

The agency is strengthening an existing warning that constipation caused by clozapine can uncommonly progress to serious bowel complications that can lead to hospitalization or death if not diagnosed and treated quickly.