In the News

Antibiotic use in early or middle adulthood associated with colorectal adenoma later in life

Researchers used data from the Nurses' Health Study to evaluate the association between colorectal adenomas and antibiotic use at ages 20 to 39 years, at ages 40 to 59 years, or within the past four years.

Risk of liver-related death linked to increased fibrosis stage in NAFLD

The systematic review and meta-analysis included five studies of 1,495 adult patients with nonalcoholic fatty liver disease (NAFLD), encompassing 17,452 patient-years of follow-up.

IBS-D drug worked better than placebo in patients already using loperamide

The industry-funded analysis looked at two phase 3 randomized, controlled trials of patients who were randomized to placebo or eluxadoline (75 or 100 mg) twice daily for 26 or 52 weeks.

MKSAP quiz: Colonoscopy after a sessile serrated polyp

This month's quiz asks readers to determine the appropriate interval for repeating colonoscopy in a 57-year-old woman whose most recent screening colonoscopy disclosed a 12-mm sessile serrated polyp in the ascending colon.

Spotlight on gastric acid suppressants

Use of gastric acid suppressants was linked with increased risk of recurrent Clostridium difficile infection and of first-time ischemic stroke in recent research.

Glasgow Blatchford score predicted intervention or death better than 4 other prediction models in upper GI bleeding

Commentary authors writing in ACP Journal Club said the findings add to a growing body of literature that supports the use of the Glasgow Blatchford score for selecting low-risk patients who can safely be discharged from the ED (with a minimal false-negative rate).