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In the Clinic, 2023 summary highlight gastroenterology topics

Colorectal cancer screening was the focus of the latest In the Clinic article, while an article in a supplement to Annals reviewed clinically important developments in gastroenterology and hepatology in 2023.
https://gastroenterology.acponline.org/archives/2024/04/26/5.htm
26 Apr 2024

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ACP Gastroenterology Monthly delivers a monthly summary of news in gastroenterology and hepatology, including the latest research, clinical guidelines, and FDA drug actions.
https://gastroenterology.acponline.org/subscribe/index.html

Adding baclofen may improve GERD symptoms, but long-term use may increase side effects

Add-on therapy with baclofen reduced reflux symptoms among patients with refractory gastroesophageal reflux disease (GERD) but prolonged use led to an increased incidence of side effects and failed to effectively reduce acid reflux occurrence, a review found.
https://gastroenterology.acponline.org/archives/2024/06/28/3.htm
28 Jun 2024

Despite guidelines, some patients opt for second fecal blood test following positive result

Although the proportion of patients who repeat tests after receiving a positive result for colorectal cancer is low, at 7.4%, among those that do repeat tests, less than half go on to receive a colonoscopy, according to a study carried out across four large health systems.
https://gastroenterology.acponline.org/archives/2024/06/28/2.htm
28 Jun 2024

Gastro experts offer best practice advice on iron to treat anemia

The American Gastroenterological Association issued a clinical practice update on management of iron-deficiency anemia, including when to use oral versus IV iron and how to handle anemia related to GI conditions.
https://gastroenterology.acponline.org/archives/2024/06/28/1.htm
28 Jun 2024

Higher MAP linked with AKI reversal among hospitalized patients

A 5 mm Hg increase in mean arterial pressure (MAP) was linked with a small but significant increase in the likelihood of reversal of acute kidney injury (AKI), according to a retrospective study of patients hospitalized with decompensated cirrhosis.
https://gastroenterology.acponline.org/archives/2024/04/26/2.htm
26 Apr 2024

GLP-1 receptor agonists could modestly delay gastric emptying during periprocedural fasting, study suggests

A systematic review and meta-analysis found that glucagon-like peptide-1 (GLP-1) receptor agonists were associated with a delay of approximately 36 minutes in gastric emptying on scintigraphy compared to placebo.
https://gastroenterology.acponline.org/archives/2024/04/26/3.htm
26 Apr 2024

Colectomy linked with greater risk of AKI, kidney failure in patients with IBD

Among patients with inflammatory bowel disease (IBD), colectomy was linked with more than doubled risk of acute kidney injury (AKI), indicating that these patients may benefit from close monitoring of kidney biomarkers, according to the authors of a Swedish cohort study.
https://gastroenterology.acponline.org/archives/2024/05/24/3.htm
24 May 2024

GLP-1s associated with lower risk of hepatic decompensation than other diabetes drugs

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes had lower risk of hepatocellular carcinoma than those on insulin or sulfonylureas, and hepatic decompensation risk was reduced compared with five comparison diabetes drug classes, a study found.
https://gastroenterology.acponline.org/archives/2024/05/24/2.htm
24 May 2024

Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation

Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024

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