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KDIGO updates guidelines on treating hepatitis C in chronic kidney disease

The latest recommendations from Kidney Disease: Improving Global Outcomes (KDIGO), which were recently summarized in Annals, address sofosbuvir treatment in patients with advanced chronic kidney disease, among other topics.
https://gastroenterology.acponline.org/archives/2023/12/22/6.htm
22 Dec 2023

Patient navigation associated with increased care, treatment in hepatitis C

A pre-post study in a safety-net health system found higher odds of linkage to care and direct-acting antiviral treatment in older adults who received patient navigation rather than usual care.
https://gastroenterology.acponline.org/archives/2022/05/27/3.htm
27 May 2022

USPSTF expands hepatitis C screening recommendation to most adults

All adults ages 18 to 79 years should now be screened at least once, but people who use injection drugs and pregnant women may require screening more often.
https://gastroenterology.acponline.org/archives/2020/03/27/6.htm
27 Mar 2020

USPSTF recommends screening adults 18 to 79 years for hepatitis C virus infection with moderate certainty

An essential requirement of expanded screening is the availability of effective treatment, but randomized controlled trials to date have not shown clinical benefit of direct-acting antiviral therapy beyond sustained virologic response, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2020/07/24/7.htm
24 Jul 2020

Hepatitis C medicines have led to liver decompensation in some patients

The FDA has identified 63 cases of liver decompensation with medications to treat hepatitis C, most of which occurred in patients with moderate to severe liver impairment who should not have been prescribed the drugs.
https://gastroenterology.acponline.org/archives/2019/09/27/6.htm
27 Sep 2019

MKSAP quiz: Complications of hepatitis C-related cirrhosis

This month's quiz asks readers to evaluate a 58-year-old man at a follow-up visit for hepatitis C-related cirrhosis complicated by nonbleeding small esophageal varices and ascites.
https://gastroenterology.acponline.org/archives/2017/07/28/4.htm
28 Jul 2017

Alcohol abstinence not required for direct-acting antivirals to cure HCV, study finds

Restricting access to direct-acting antiviral therapy because of alcohol use creates an unnecessary barrier for patients with hepatitis C virus (HCV) infection, according to the authors of a recent study.
https://gastroenterology.acponline.org/archives/2023/10/27/1.htm
27 Oct 2023

ACP and the American Academy of HIV Medicine collaborate on new guide to hepatitis C testing

The guide includes a summary of the latest testing recommendations; diagnostic, billing, and laboratory codes for testing; resources for referrals to HCV-experienced clinicians; and information on patient interactions, education, conversations, and case examples.
https://gastroenterology.acponline.org/archives/2017/05/26/6.htm
26 May 2017

About one-third of Americans with HCV had evidence of viral clearance in past decade

The highest proportion of hepatitis C virus (HCV) cure or clearance among all age groups and payers was 49% among commercially insured patients ages 60 years and older, a study found.
https://gastroenterology.acponline.org/archives/2023/07/28/6.htm
28 Jul 2023

Reformulation of extended-release oxycodone may have triggered increase in hepatitis C rates

Hepatitis C virus infections increased three times faster in states with above-median rates of initial misuse of extended-release oxycodone (OxyContin) than in states with below-median rates, and the increase began immediately after a reformulation of the drug in 2010.
https://gastroenterology.acponline.org/archives/2019/02/22/1.htm
22 Feb 2019

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