Search results for "GI bleeding"
Restricting PPI prescription refills reduced use without noticeable clinical effects
Restrictions on proton-pump inhibitor (PPI) refills for patients without a documented long-term indication were associated with a rapid and sustained 7.3% absolute reduction in such prescriptions—a relative decline of nearly 30%, a Veterans Affairs study found.
https://gastroenterology.acponline.org/archives/2024/04/26/1.htm
26 Apr 2024
Case report details serious, recurrent GI bleeding associated with sotatercept
The investigational medication is being evaluated for use in patients with pulmonary arterial hypertension.
https://gastroenterology.acponline.org/archives/2024/01/26/6.htm
26 Jan 2024
Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation
Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024
ACG updates its guideline on acute lower GI bleeding
The American College of Gastroenterology (ACG) now recommends risk stratification to identify patients who can be discharged early and advises on the use of anticoagulant reversal agents, among other changes.
https://gastroenterology.acponline.org/archives/2023/03/24/2.htm
24 Mar 2023
Early colonoscopy did not improve outcomes in those hospitalized for lower GI bleeding
A meta-analysis included four randomized trials comparing outcomes of colonoscopy within 24 hours versus later elective colonoscopy and/or other diagnostic tests in patients with lower gastrointestinal (GI) bleeding.
https://gastroenterology.acponline.org/archives/2019/12/27/3.htm
27 Dec 2019
Manage meds to treat GI bleeding before, after endoscopy
Care of inpatients with GI bleeding is complicated and multidisciplinary, but hospitalists can contribute by starting and stopping the right drugs, according to conference coverage from Internal Medicine Meeting 2022.
https://gastroenterology.acponline.org/archives/2022/05/27/6.htm
27 May 2022
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
Apixaban associated with lower risk of GI bleeding compared to other DOACs
Apixaban users experienced similar rates of ischemic stroke or systemic embolism, intracranial hemorrhage, and all-cause mortality as patients taking other direct oral anticoagulants (DOACs), a retrospective analysis found.
https://gastroenterology.acponline.org/archives/2022/11/18/6.htm
18 Nov 2022
Over-the-scope clips may be better initial treatment than standard hemostatic treatment in patients with nonvariceal upper GI bleeding
In a randomized controlled trial of 190 adults, 30-day probability of further bleeding was significantly lower in patients who received over-the-scope clips than in those who received standard endoscopic hemostatic treatment.
https://gastroenterology.acponline.org/archives/2023/03/24/10.htm
24 Mar 2023
Two risk scores most accurately predict outcomes after lower GI bleeding
The Oakland score performed best for predicting safe discharge, major bleeding, and transfusion, while the Strate score performed best for hemostasis, according to a recent review and meta-analysis that assessed four scores.
https://gastroenterology.acponline.org/archives/2022/06/24/6.htm
24 Jun 2022