Search results for "From ACP Journal Club"
Recommendations for pharmacologic management of IBS with diarrhea, constipation
New guidelines suggest that there are several effective drugs available for irritable bowel syndrome (IBS), but a more detailed analysis indicates that the best treatments increase the rate of response by only 15% versus placebo, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2022/11/18/8.htm
18 Nov 2022
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
In active UC, upadacitinib induced and maintained remission
JAK inhibitors, such as upadacitinib, represent an advance in the management of patients with ulcerative colitis (UC); however, it remains unclear whether the balance of efficacy versus risk favors one drug over the others, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2022/10/28/11.htm
28 Oct 2022
In drug-refractory IBS, group CBT with interoceptive exposure improved symptoms and quality of life at 13 wk
Given the results of this small, randomized trial, a head-to-head comparison of multidisciplinary care versus group cognitive behavioral therapy (CBT) delivered over the internet for patients with irritable bowel syndrome (IBS) is now warranted, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2022/08/26/10.htm
26 Aug 2022
In active Crohn disease, risankizumab increased clinical remission and endoscopic response at 12 wk
While the FDA has now approved risankizumab for adults with moderate to severe Crohn disease, understanding of the drug's role in relation to other biologic therapies is limited by broad exclusion criteria in randomized controlled trials, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2022/10/28/10.htm
28 Oct 2022
ACG-CAG provided suggestions for periendoscopic management of anticoagulants and antiplatelets
The recommendations from the American College of Gastroenterology (ACG) and the Canadian Association of Gastroenterology (CAG), particularly those for withholding antithrombotics before planned endoscopic procedures, require individualized decision making with multidisciplinary input, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2022/07/22/7.htm
22 Jul 2022
Aspirin use is associated with reduced risk for hepatocellular carcinoma
The findings of a recent meta-analysis provide support for an association between aspirin use and reduced risk for hepatocellular carcinoma but do not warrant use of aspirin as prophylaxis, and more research is needed, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2022/07/22/8.htm
22 Jul 2022
In IBS, a smartphone application for self-managing a FODMAP-lowering diet vs. otilonium bromide reduced symptoms at 8 wk
Delivery of a fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP)-lowering dietary intervention via an app may help educate patients about diet and augment the clinician-patient relationship, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2022/08/26/9.htm
26 Aug 2022
Invitation to a single FS screening vs. usual care reduced colorectal cancer mortality and incidence at >15 y
The SCORE trial demonstrated the long-term protective effect from flexible sigmoidoscopy (FS) screening for colorectal cancer at ages 55 to 64 years, supporting the safety of using it as a single intervention, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2022/03/25/7.htm
25 Mar 2022
In mild acute diverticulitis, outpatient therapy without antibiotics was noninferior to antibiotics
The DINAMO-study is the first outpatient trial to show that withholding antibiotics may not have inferior outcomes, although the results may be partly explained by use of NSAIDs and/or acetaminophen in both groups, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2022/02/25/9.htm
25 Feb 2022