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Lowering colorectal cancer screening age from 50 to 45 years appears cost-effective

Initiating screening at age 45 years would require an additional 10 million colonoscopies, which could potentially provide greater benefit if used instead to increase screening rates in older patients, authors of the modeling study said.
https://gastroenterology.acponline.org/archives/2019/04/26/1.htm
26 Apr 2019

In Barrett esophagus, high- vs low-dose esomeprazole improved clinical outcomes; aspirin vs no aspirin did not

The safety of high-dose proton-pump inhibitor therapy is probably acceptable, but the addition of aspirin carries more risk, has less evidence on efficacy, and needs an individualized approach, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2018/12/28/10.htm
28 Dec 2018

In the Clinic: Nonalcoholic fatty liver disease

This feature provides an evidence-based, clinically relevant overview of the diagnosis and treatment of nonalcoholic fatty liver disease.
https://gastroenterology.acponline.org/archives/2018/11/27/8.htm
27 Nov 2018

Tailored thresholds for FIT may increase colorectal cancer detection

Rates of cancer detection and the number of positive test results per cancer case detected varied significantly by age and sex, which suggests that modifying positivity thresholds by subgroups might optimize screening program performance.
https://gastroenterology.acponline.org/archives/2018/09/28/6.htm
28 Sep 2018

Rates of HDV co-infection may be higher than previously estimated

Patients with chronic hepatitis B virus (HBV) and hepatitis D virus (HDV) co-infection have the most severe form of viral hepatitis and are at much higher risk for cirrhosis and hepatocellular cancer than patients with HBV infection alone.
https://gastroenterology.acponline.org/archives/2018/09/28/3.htm
28 Sep 2018

Topic-specific resources available through ACP Online Learning Center

The learning center provides access to a curated collection of more than 400 online learning activities and includes a section focused specifically on gastroenterology and hepatology.
https://gastroenterology.acponline.org/archives/2018/05/25/8.htm
25 May 2018

In the Clinic: Acute diverticulitis

A recent In the Clinic article offered a clinically relevant overview of the epidemiology, diagnosis, and treatment of acute diverticulitis.
https://gastroenterology.acponline.org/archives/2018/05/25/9.htm
25 May 2018

Fecal transplants by pill noninferior to colonoscopy delivery

The primary outcome of the unblinded, randomized trial was the proportion of patients without recurrent Clostridium difficile infection 12 weeks after fecal transplant.
https://gastroenterology.acponline.org/archives/2017/12/22/1.htm
22 Dec 2017

Spotlight on screening in primary care

Patient-specific reminders for clinicians performed best for increasing colorectal cancer screening in a French study, while an EHR alert appeared to successfully increase hepatitis C virus screening rates for baby boomers in a U.S. health care system.
https://gastroenterology.acponline.org/archives/2017/09/22/5.htm
22 Sep 2017

AGA releases recommendations on therapeutic drug monitoring in IBD

The recommendations call for drug monitoring in patients with active inflammatory bowel disease (IBD) who are starting thiopurines or having potentially related adverse events, among other recommendations.
https://gastroenterology.acponline.org/archives/2017/08/25/1.htm
25 Aug 2017

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