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Sort by: Relevance | Newest | Oldest8 weeks of ledipasvir/sofosbuvir may be effective for genotype 1 hepatitis C
The therapy should be considered in patients with genotype 1 infection who are treatment-naive, do not have cirrhosis, and have a pretreatment viral load below 6,000,000 IU/mL, a study found.
https://gastroenterology.acponline.org/archives/2017/03/24/2.htm
24 Mar 2017
High HCV cure rate seen with FDA-approved direct-acting antiviral regimens
Six of the direct-acting antiviral (DAA) regimens yielded sustained virologic response rates above 95% in patients who had hepatitis C virus (HCV) genotype 1 without cirrhosis, including those with HIV co-infection.
https://gastroenterology.acponline.org/archives/2017/03/24/7.htm
24 Mar 2017
ACP and the American Academy of HIV Medicine collaborate on new guide to hepatitis C testing
The guide includes a summary of the latest testing recommendations; diagnostic, billing, and laboratory codes for testing; resources for referrals to HCV-experienced clinicians; and information on patient interactions, education, conversations, and case examples.
https://gastroenterology.acponline.org/archives/2017/05/26/6.htm
26 May 2017
Spotlight on statin therapy
Studies published in May found a potential benefit of statin therapy for three different conditions.
https://gastroenterology.acponline.org/archives/2017/05/26/5.htm
26 May 2017
Study finds substantial increase in HCV infection among younger women, children
Data from the National Notifiable Diseases Surveillance System and the Quest Diagnostics Health Trends database were used to estimate the incidence of hepatitis C virus (HCV) infection among women ages 15 to 44 years and children ages 2 to 13 years.
https://gastroenterology.acponline.org/archives/2017/05/26/1.htm
26 May 2017
HCV treatment appeared successful for patients who hadn't responded to previous direct-acting antivirals, industry-funded study finds
The study included two phase 3 trials: POLARIS-1, in which patients with chronic hepatitis C virus (HCV) had previously taken a regimen containing an NS5A inhibitor, and POLARIS-4, in which patients had previously received a direct-acting antiviral agent regimen that did not include an NS5A inhibitor.
https://gastroenterology.acponline.org/archives/2017/06/23/3.htm
23 Jun 2017
MKSAP quiz: Complications of hepatitis C-related cirrhosis
This month's quiz asks readers to evaluate a 58-year-old man at a follow-up visit for hepatitis C-related cirrhosis complicated by nonbleeding small esophageal varices and ascites.
https://gastroenterology.acponline.org/archives/2017/07/28/4.htm
28 Jul 2017
Review: In chronic hepatitis C virus infection, oral direct-acting antivirals have high sustained virologic response
A commentary in ACP Journal Club noted that while screening and treating all patients with chronic hepatitis C virus (HCV) would be cost-effective and probably cost-saving, some payers are still resistant.
https://gastroenterology.acponline.org/archives/2017/07/28/11.htm
28 Jul 2017
New HCV drug combo approved
The fixed-dose tablet combines the previously approved drugs sofosbuvir and velpatasvir with a new drug, voxilaprevir.
https://gastroenterology.acponline.org/archives/2017/07/28/10.htm
28 Jul 2017
Nearly all patients in study achieved sustained virologic response after 12 weeks of new HCV treatment
The drug combination appeared effective in adults with HCV genotypes 1, 2, 4, 5, or 6 infection and compensated cirrhosis in the industry-funded trial.
https://gastroenterology.acponline.org/archives/2017/08/25/3.htm
25 Aug 2017