Search results for "Highlights"
Use of PPIs may be associated with C. difficile infections
A Danish nationwide cohort study found that ongoing exposure to proton-pump inhibitors (PPIs) was associated with moderately increased community-associated Clostridioides difficile infection risk during treatment and for up to one year afterward.
https://gastroenterology.acponline.org/archives/2021/03/26/3.htm
26 Mar 2021
Systematic review compares over-the-counter treatments for chronic constipation
Polyethylene glycol and senna had good evidence for their use as first-line laxatives, while moderate evidence supported fiber supplements, fruits, stimulant laxatives, and magnesium-based products.
https://gastroenterology.acponline.org/archives/2021/06/25/3.htm
25 Jun 2021
Noninvasive score for fibrotic NASH designed for, validated in primary care settings
Levels of aspartate aminotransferase, high-density lipoprotein cholesterol, and HbA1c can be used to predict which patients might need referral to a subspecialist for fibrotic nonalcoholic steatohepatitis (NASH).
https://gastroenterology.acponline.org/archives/2022/04/22/1.htm
22 Apr 2022
Spotlight on The Liver Meeting
Highlights from the American Association for the Study of Liver Diseases' annual meeting, held virtually this past weekend, included insights on COVID-19 and the liver and a conversation with the winners of the Nobel Prize in Physiology or Medicine 2020, who discovered hepatitis C virus.
https://gastroenterology.acponline.org/archives/2020/11/20/5.htm
20 Nov 2020
Practice guidance addresses vascular liver disorders, portal vein thrombosis, procedural bleeding
Among other statements, the American Association for the Study of Liver Diseases said that modifiable risk factors for bleeding, such as use of antithrombotic drugs, should be identified and corrected before procedures in patients with cirrhosis.
https://gastroenterology.acponline.org/archives/2020/12/18/2.htm
18 Dec 2020
Tenofovir alafenamide may safely replace tenofovir disoproxil fumarate in patients with drug-resistant HBV, trial finds
An industry-funded randomized trial found that tenofovir alafenamide could be substituted for tenofovir disoproxil fumarate in patients with multidrug-resistant hepatitis B virus (HBV) for improved bone and renal safety without a loss of efficacy; however, the former drug was associated with greater increases in body weight and cholesterol levels.
https://gastroenterology.acponline.org/archives/2021/05/28/4.htm
28 May 2021
Urgent endoscopy did not improve outcomes from acute upper GI bleeds
Thirty-day mortality was slightly lower among high-risk patients who underwent endoscopy for an acute upper GI bleed within 24 hours of a consult instead of within six hours, although the difference was not statistically significant.
https://gastroenterology.acponline.org/archives/2020/04/24/3.htm
24 Apr 2020
Infliximab or tofacitinib for IBD associated with lower response to COVID-19 vaccination
An industry-funded study in England looked at SARS-CoV-2 antibody concentrations after two vaccine doses among patients taking infliximab, tofacitinib, thiopurine, ustekinumab, or vedolizumab for inflammatory bowel disease (IBD), comparing them to healthy controls.
https://gastroenterology.acponline.org/archives/2022/02/25/1.htm
25 Feb 2022
AGA issues guidelines on use of intragastric balloon therapy for patients with obesity
Intragastric balloon therapy can be considered as a weight loss intervention in patients with obesity who have not seen success with conventional therapies, according to the American Gastroenterological Association (AGA).
https://gastroenterology.acponline.org/archives/2021/04/23/2.htm
23 Apr 2021
Amoxicillin-clavulanate appears safe, effective for diverticulitis in outpatients
A retrospective cohort study compared amoxicillin-clavulanate with metronidazole-fluoroquinolone and found no differences in outcomes including risks for inpatient admission or surgery, while Clostridioides difficile risk appeared higher in older patients on the latter regimen.
https://gastroenterology.acponline.org/archives/2021/02/26/2.htm
26 Feb 2021