Search results for "Highlights"
GI bleeding less common in U.S. veterans on NOACs than those on warfarin
Significant bleeding occurred in 2.5% of the patients on warfarin and 0.6% of the patients on non-vitamin K antagonist oral anticoagulants (NOACs).
https://gastroenterology.acponline.org/archives/2017/03/24/3.htm
24 Mar 2017
Pioglitazone associated with improved advanced fibrosis in patients with NASH
A recent meta-analysis looked at randomized clinical trials that examined the effect of thiazolidinediones on liver histology in patients with nonalcoholic steatohepatitis (NASH).
https://gastroenterology.acponline.org/archives/2017/03/24/1.htm
24 Mar 2017
Tofacitinib more effective than placebo for ulcerative colitis, industry-funded study finds
The drug was evaluated in three multicenter, phase 3, randomized, double-blind, placebo-controlled trials involving patients with moderately to severely active disease.
https://gastroenterology.acponline.org/archives/2017/05/26/2.htm
26 May 2017
Anticoagulants safe, effective in cirrhosis with portal vein thrombosis, review finds
Researchers analyzed eight studies with 353 patients to assess the effect of low-molecular-weight heparin or warfarin on recanalization, thrombosis progression, and bleeding.
https://gastroenterology.acponline.org/archives/2017/05/26/3.htm
26 May 2017
Study finds substantial increase in HCV infection among younger women, children
Data from the National Notifiable Diseases Surveillance System and the Quest Diagnostics Health Trends database were used to estimate the incidence of hepatitis C virus (HCV) infection among women ages 15 to 44 years and children ages 2 to 13 years.
https://gastroenterology.acponline.org/archives/2017/05/26/1.htm
26 May 2017
Spotlight on nonalcoholic fatty liver disease and cardiac risk
Studies published in August examined the association between nonalcoholic steatohepatitis and heart failure and the effect of alcohol on cardiovascular risk in patients with nonalcoholic fatty liver disease.
https://gastroenterology.acponline.org/archives/2017/08/25/5.htm
25 Aug 2017
Boxed warning added to liver disease drug
The drug has been incorrectly dosed daily instead of weekly in patients with moderate to severe primary biliary cholangitis, which increases the risk of serious liver injury, the FDA said.
https://gastroenterology.acponline.org/archives/2018/02/23/7.htm
23 Feb 2018
Spotlight on esophageal adenocarcinoma
High-dose proton-pump inhibitors and aspirin appeared effective for chemoprevention in patients with Barrett's esophagus in one study, while another study found a positive association between human papillomavirus status and survival in patients with Barrett's high-grade dysplasia and esophageal adenocarcinoma.
https://gastroenterology.acponline.org/archives/2018/08/24/5.htm
24 Aug 2018
Induction, maintenance therapies for ulcerative colitis compared
Oral sulfasalazine, diazo-bonded 5-aminosalicylates (5-ASAs), mesalazine, controlled ileal-release budesonide, and budesonide multimatrix, alone or in combination with rectal 5-ASA therapy, were assessed for comparative efficacy and tolerability.
https://gastroenterology.acponline.org/archives/2018/08/24/3.htm
24 Aug 2018
Beta-blocker monotherapy may be preferred for primary prophylaxis of esophageal variceal bleeding
Guidelines currently recommend nonselective beta-blockers or variceal band ligation for primary prevention of variceal bleeding based on similar efficacy, but survival benefit may be better with the former treatment.
https://gastroenterology.acponline.org/archives/2018/08/24/2.htm
24 Aug 2018