Search results for "Highlights"
Tenofovir alafenamide may safely replace tenofovir disoproxil fumarate in patients with drug-resistant HBV, trial finds
An industry-funded randomized trial found that tenofovir alafenamide could be substituted for tenofovir disoproxil fumarate in patients with multidrug-resistant hepatitis B virus (HBV) for improved bone and renal safety without a loss of efficacy; however, the former drug was associated with greater increases in body weight and cholesterol levels.
https://gastroenterology.acponline.org/archives/2021/05/28/4.htm
28 May 2021
Amoxicillin-clavulanate appears safe, effective for diverticulitis in outpatients
A retrospective cohort study compared amoxicillin-clavulanate with metronidazole-fluoroquinolone and found no differences in outcomes including risks for inpatient admission or surgery, while Clostridioides difficile risk appeared higher in older patients on the latter regimen.
https://gastroenterology.acponline.org/archives/2021/02/26/2.htm
26 Feb 2021
Metabolic syndrome may be linked to pancreatic cancer risk
A nationwide cohort study in Korea found that risk for pancreatic cancer decreased in patients whose metabolic syndrome improved versus persisted over time.
https://gastroenterology.acponline.org/archives/2021/10/22/2.htm
22 Oct 2021
Noninvasive score for fibrotic NASH designed for, validated in primary care settings
Levels of aspartate aminotransferase, high-density lipoprotein cholesterol, and HbA1c can be used to predict which patients might need referral to a subspecialist for fibrotic nonalcoholic steatohepatitis (NASH).
https://gastroenterology.acponline.org/archives/2022/04/22/1.htm
22 Apr 2022
Systematic review compares over-the-counter treatments for chronic constipation
Polyethylene glycol and senna had good evidence for their use as first-line laxatives, while moderate evidence supported fiber supplements, fruits, stimulant laxatives, and magnesium-based products.
https://gastroenterology.acponline.org/archives/2021/06/25/3.htm
25 Jun 2021
AGA issues guidelines on use of intragastric balloon therapy for patients with obesity
Intragastric balloon therapy can be considered as a weight loss intervention in patients with obesity who have not seen success with conventional therapies, according to the American Gastroenterological Association (AGA).
https://gastroenterology.acponline.org/archives/2021/04/23/2.htm
23 Apr 2021
Guideline from CRC task force recommends starting screening at ages 45 to 49 years in all average-risk patients
Increasing disease incidence and a favorable harm-benefit ratio are two reasons to expand the age range for colorectal cancer (CRC) screening to younger patients, a task force determined.
https://gastroenterology.acponline.org/archives/2021/11/19/1.htm
19 Nov 2021
Infliximab or tofacitinib for IBD associated with lower response to COVID-19 vaccination
An industry-funded study in England looked at SARS-CoV-2 antibody concentrations after two vaccine doses among patients taking infliximab, tofacitinib, thiopurine, ustekinumab, or vedolizumab for inflammatory bowel disease (IBD), comparing them to healthy controls.
https://gastroenterology.acponline.org/archives/2022/02/25/1.htm
25 Feb 2022
U.S. antibiotic resistance rates for H. pylori appear high
A systematic review and meta-analysis of resistance patterns of Helicobacter pylori strains found that resistance to metronidazole, levofloxacin, and clarithromycin exceeds 30%.
https://gastroenterology.acponline.org/archives/2022/05/27/1.htm
27 May 2022
Q&A: A deeper dive into ACP's new diverticulitis guidelines
Authors discussed the College's first clinical guidelines on diagnosis and management of diverticulitis, which provide recommendations on when to use imaging, antibiotics, colonoscopy, and other interventions.
https://gastroenterology.acponline.org/archives/2022/01/28/1.htm
28 Jan 2022