Search results for "GERD"
In US veterans, PPIs were linked to increased all-cause and some cause-specific mortality compared with H2-blockers
The observational study cannot establish causation, and the only way to prove that proton-pump inhibitors (PPIs) cause the various adverse outcomes attributed to them is to compare them with placebo or no treatment in a randomized trial, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2019/09/27/11.htm
27 Sep 2019
Probable carcinogen found in some ranitidine medicines
While the FDA is not calling for individuals to stop taking ranitidine at this time, it said that patients who wish to discontinue prescription use should talk to their clinician about other treatment options.
https://gastroenterology.acponline.org/archives/2019/09/27/9.htm
27 Sep 2019
MKSAP quiz: Management of atypical chest pain
This month's quiz asks readers to determine the most appropriate course of management for a 56-year-old woman with chest discomfort that intermittently occurs after meals and while walking up stairs.
https://gastroenterology.acponline.org/archives/2019/10/25/4.htm
25 Oct 2019
Many patients with ‘refractory’ heartburn successfully treated with PPI regimen
Among study participants whose reflux-related heartburn truly did not respond to a proton-pump inhibitor (PPI), surgery (laparoscopic Nissen fundoplication) was more effective than medical therapy (omeprazole and baclofen plus desipramine if needed).
https://gastroenterology.acponline.org/archives/2019/10/25/1.htm
25 Oct 2019
MKSAP Quiz: 3-month history of dysphagia, regurgitation
A 52-year-old man is evaluated for dysphagia of 3 months' duration. He reports regurgitating undigested food soon after eating solid food, occasional coughing and choking after swallowing, and chronic halitosis. What is the most appropriate diagnostic test to perform next?
https://gastroenterology.acponline.org/archives/2020/02/28/4.htm
28 Feb 2020
Internists may overestimate risks of PPIs, survey suggests
A survey of internists showed that 79% inappropriately recommended stopping proton-pump inhibitors (PPIs) in a prevention scenario focusing on high-risk upper gastrointestinal bleeding.
https://gastroenterology.acponline.org/archives/2020/02/28/3.htm
28 Feb 2020
In reflux-related heartburn unresponsive to PPIs, surgery increased treatment success vs active medical treatment
An ACP Journal Club commentary noted that physicians should not change their practice based on the results of the trial, which are in contrast to the literature and expert opinion, until they are confirmed by studies assessing objective primary end points.
https://gastroenterology.acponline.org/archives/2020/03/27/12.htm
27 Mar 2020
Spotlight on screening for Barrett's esophagus
Recent studies looked at a nonendoscopic test for Barrett's esophagus in primary care, as well as screening for the condition before and after gastric bypass procedures.
https://gastroenterology.acponline.org/archives/2020/08/28/5.htm
28 Aug 2020
Wireless monitoring identified patients who could discontinue PPIs
Patients with reflux symptoms and inadequate response to proton-pump inhibitors (PPIs) discontinued the drugs for a week and then had their acid exposure time measured by a wireless pH capsule in a recent study.
https://gastroenterology.acponline.org/archives/2020/09/25/3.htm
25 Sep 2020
Sessions from ACG 2020 tackled persistent GERD, acute colonic pseudo-obstruction
Coverage of the American College of Gastroenterology's annual meeting in the February ACP Internist and ACP Hospitalist offered advice on managing patients with persistent gastroesophageal reflux disease (GERD) and recognizing acute colonic pseudo-obstruction.
https://gastroenterology.acponline.org/archives/2021/02/26/6.htm
26 Feb 2021