Search results for "From ACP Journal Club"

Results 11 - 20 of about 41 for "From ACP Journal Club".
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In mild acute diverticulitis, outpatient therapy without antibiotics was noninferior to antibiotics

The DINAMO-study is the first outpatient trial to show that withholding antibiotics may not have inferior outcomes, although the results may be partly explained by use of NSAIDs and/or acetaminophen in both groups, an ACP Journal Club commentary noted.
25 Feb 2022

Vonoprazan-containing therapy has an H pylori eradication rate >90% and increases eradication vs. standard triple therapy

Results of a systematic review and network meta-analysis support a shift toward a susceptibility-based approach to Helicobacter pylori infection based on principles of antimicrobial stewardship, an ACP Journal Club commentary noted.
22 Oct 2021

Daily aspirin for primary CVD prevention increased risk for major GI bleeding in healthy older adults

While aspirin is not recommended for primary prevention of cardiovascular disease (CVD) in most adults ages 70 years and older, more research is needed to assess its role in select high-risk populations of older adults, an ACP Journal Club commentary said.
22 Jan 2021

USPSTF recommends screening adults 18 to 79 years for hepatitis C virus infection with moderate certainty

An essential requirement of expanded screening is the availability of effective treatment, but randomized controlled trials to date have not shown clinical benefit of direct-acting antiviral therapy beyond sustained virologic response, an ACP Journal Club commentary noted.
24 Jul 2020

In patients having transjugular intrahepatic portosystemic shunt, rifaximin prevented overt hepatic encephalopathy

Results from a French trial provide the best available evidence to justify using the expensive antibiotic in patients with hepatic encephalopathy associated with transjugular intrahepatic portosystemic shunt, according to an ACP Journal Club commentary.
23 Jul 2021

In recurrent C difficile infection, oral FMT capsules have a pooled cure rate of 82% (low-quality evidence)

While the findings of a recent study are promising for oral fecal microbiota transplantation (FMT) capsules to treat patients with recurrent Clostridioides difficile infection, more well-designed trials are needed before routine use, an ACP Journal Club commentary noted.
25 Jun 2021

Any of 4 screening options suggested for screen-naive adults 59 to 70 y with ≥ 3% 15-y risk for colorectal cancer

To balance shared decision making and population health in colorectal cancer screening, as called for in a recent guideline, a viable strategy could include universal, opt-out fecal immunochemical testing starting at age 50 years, a commentary in ACP Journal Club noted.
27 Mar 2020

Aspirin before fecal immunochemical testing did not increase sensitivity for detecting advanced colorectal neoplasms

The results of the randomized trial do not support routinely recommending aspirin before fecal immunochemical testing for colorectal cancer screening, according to an ACP Journal Club commentary.
23 Aug 2019

Cholecystectomy reduced major complications vs catheter drainage in high-risk patients with acute cholecystitis

A Dutch trial showed that older patients without life-threatening comorbidities may benefit from early surgical intervention, but the results would be more generalizable if the study had included patients from a broader age range, an ACP Journal Club commentary said.
22 Mar 2019

In adults with severe acute GI bleeding, tranexamic acid did not reduce death due to bleeding at 5 days

Based on findings from a randomized trial, tranexamic acid is unlikely to confer additional benefit beyond the current standard of care in all patients with severe upper or lower GI bleeding, an ACP Journal Club commentary said.
23 Oct 2020

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