Search results for "Infectious diseases"
Patients with discordant C. difficile test results had lower mortality with treatment
Patients who were positive for Clostridioides difficile on nucleic acid amplification testing but negative on toxin immunoassay had similar 30-day mortality to those with positive results on both tests, according to a review of observational studies.
https://gastroenterology.acponline.org/archives/2023/09/22/7.htm
22 Sep 2023
How would you manage this patient with Clostridioides difficile infection?
An infectious diseases specialist and a gastroenterologist discussed antibiotic treatment options for nonsevere Clostridioides difficile in a recent Beyond the Guidelines.
https://gastroenterology.acponline.org/archives/2023/08/25/10.htm
25 Aug 2023
ID, liver societies update guidance for HCV testing, management
Major changes to guidance on hepatitis C virus (HCV) include an emphasis on universal screening, new recommendations for managing incomplete treatment adherence, and expansion of treatment eligibility, among others.
https://gastroenterology.acponline.org/archives/2023/06/23/6.htm
23 Jun 2023
Two-step testing for Clostridioides difficile appears safe in multicenter study
Using an enzyme immunoassay after a positive nucleic acid amplification test was associated with a decrease in hospital-onset Clostridioides difficile infections and a reduction in related antibiotic use but no change in emergent colectomies.
https://gastroenterology.acponline.org/archives/2023/06/23/7.htm
23 Jun 2023
Mandatory approval process for C. diff testing linked to lower hospital-onset infection rates
An intervention that required mandatory approval from an infectious diseases physician before testing for Clostridioides difficile was associated with a greater than 50% decrease in hospital-onset C. difficile infection rates at one hospital.
https://gastroenterology.acponline.org/archives/2023/05/26/6.htm
26 May 2023
Most asymptomatic C. difficile carriers in health care settings did not progress to infection
In a study at three U.S. hospitals and affiliated long-term care facilities, most patients who were found to be carriers of Clostridioides difficile had cleared the bacteria on subsequent testing, and only 13.4% were subsequently diagnosed with infection.
https://gastroenterology.acponline.org/archives/2023/03/24/8.htm
24 Mar 2023
Computerized clinical decision support may help reduce unnecessary C. diff testing
A two-year cohort study of nine academic and six community hospitals in the U.S. found that testing for Clostridioides difficile decreased when the electronic health record stopped a clinician from proceeding with a test order if the patient had already been tested or had recently received laxatives.
https://gastroenterology.acponline.org/archives/2022/02/25/7.htm
25 Feb 2022
Use of PPIs may be associated with C. difficile infections
A Danish nationwide cohort study found that ongoing exposure to proton-pump inhibitors (PPIs) was associated with moderately increased community-associated Clostridioides difficile infection risk during treatment and for up to one year afterward.
https://gastroenterology.acponline.org/archives/2021/03/26/3.htm
26 Mar 2021
Studies examine impact of hospital policies on C. difficile infection rates
While one study found that participation in an antibiotic stewardship program from the Agency for Healthcare Research and Quality led to reductions in hospital-onset Clostridioides difficile infection rates, a simulation study found that visitor contact precautions may not be as helpful.
https://gastroenterology.acponline.org/archives/2021/03/26/7.htm
26 Mar 2021
Effects of gastric acid suppression drugs on COVID-19 outcomes still unclear
A meta-analysis didn't find an association between famotidine use and severe disease or death from COVID-19, and the association of these outcomes with proton-pump inhibitors varied by study type.
https://gastroenterology.acponline.org/archives/2021/02/26/1.htm
26 Feb 2021