An industry-funded randomized trial found that tenofovir alafenamide could be substituted for tenofovir disoproxil fumarate in patients with multidrug-resistant hepatitis B virus (HBV) for improved bone and renal safety without a loss of efficacy;
The American Gastroenterological Association released new guidance for clinicians caring for patients with inflammatory bowel disease (IBD) and those performing endoscopic procedures, and two recent studies looked at GI symptoms in patients with
A retrospective cohort study compared amoxicillin-clavulanate with metronidazole-fluoroquinolone and found no differences in outcomes including risks for inpatient admission or surgery, while Clostridioides difficile risk appeared higher in older
Data from the National Notifiable Diseases Surveillance System and the Quest Diagnostics Health Trends database were used to estimate the incidence of hepatitis C virus (HCV) infection among women ages 15 to 44 years and children ages 2 to 13 years.
There was no significant difference in upper GI events between a pantoprazole group and a placebo group, although pantoprazole was associated with significantly reduced bleeding of gastroduodenal lesions, an industry-funded study found.
About 84% of participants randomly assigned to receive rifabutin in addition to amoxicillin and omeprazole achieved Helicobacter pylori eradication, compared to 58% of those who received amoxicillin and omeprazole alone.
Thirty-day mortality was slightly lower among high-risk patients who underwent endoscopy for an acute upper GI bleed within 24 hours of a consult instead of within six hours, although the difference was not statistically significant.
An analysis of participants in the Nurses' Health Study and the Health Professionals Follow-up Study found that more frequent bowel movements appear to be a risk factor for subsequent diverticulitis in both men and women.
The prevalence of any suspected liver fibrosis in patients with diabetes was 21% in a recent study, leading the authors to call for more aggressive screening in patients with obesity and diabetes.
Among other statements, the American Association for the Study of Liver Diseases said that modifiable risk factors for bleeding, such as use of antithrombotic drugs, should be identified and corrected before procedures in patients with cirrhosis.