Search results for "Highlights"
PPIs not associated with mortality risk for most causes, study finds
While patients who took proton-pump inhibitors (PPIs) had significantly higher risks of all-cause mortality and mortality due to cancer, cardiovascular diseases, respiratory diseases, and digestive diseases, lag times of up to six years attenuated these associations so they were no longer statistically significant.
https://gastroenterology.acponline.org/archives/2022/07/22/1.htm
22 Jul 2022
Practice guidance addresses vascular liver disorders, portal vein thrombosis, procedural bleeding
Among other statements, the American Association for the Study of Liver Diseases said that modifiable risk factors for bleeding, such as use of antithrombotic drugs, should be identified and corrected before procedures in patients with cirrhosis.
https://gastroenterology.acponline.org/archives/2020/12/18/2.htm
18 Dec 2020
Urgent endoscopy did not improve outcomes from acute upper GI bleeds
Thirty-day mortality was slightly lower among high-risk patients who underwent endoscopy for an acute upper GI bleed within 24 hours of a consult instead of within six hours, although the difference was not statistically significant.
https://gastroenterology.acponline.org/archives/2020/04/24/3.htm
24 Apr 2020
Amoxicillin-clavulanate appears safe, effective for diverticulitis in outpatients
A retrospective cohort study compared amoxicillin-clavulanate with metronidazole-fluoroquinolone and found no differences in outcomes including risks for inpatient admission or surgery, while Clostridioides difficile risk appeared higher in older patients on the latter regimen.
https://gastroenterology.acponline.org/archives/2021/02/26/2.htm
26 Feb 2021
Metabolic syndrome may be linked to pancreatic cancer risk
A nationwide cohort study in Korea found that risk for pancreatic cancer decreased in patients whose metabolic syndrome improved versus persisted over time.
https://gastroenterology.acponline.org/archives/2021/10/22/2.htm
22 Oct 2021
Tenofovir alafenamide may safely replace tenofovir disoproxil fumarate in patients with drug-resistant HBV, trial finds
An industry-funded randomized trial found that tenofovir alafenamide could be substituted for tenofovir disoproxil fumarate in patients with multidrug-resistant hepatitis B virus (HBV) for improved bone and renal safety without a loss of efficacy; however, the former drug was associated with greater increases in body weight and cholesterol levels.
https://gastroenterology.acponline.org/archives/2021/05/28/4.htm
28 May 2021
Systematic review compares over-the-counter treatments for chronic constipation
Polyethylene glycol and senna had good evidence for their use as first-line laxatives, while moderate evidence supported fiber supplements, fruits, stimulant laxatives, and magnesium-based products.
https://gastroenterology.acponline.org/archives/2021/06/25/3.htm
25 Jun 2021
More frequent bowel movements may be associated with diverticulitis risk
An analysis of participants in the Nurses' Health Study and the Health Professionals Follow-up Study found that more frequent bowel movements appear to be a risk factor for subsequent diverticulitis in both men and women.
https://gastroenterology.acponline.org/archives/2021/01/22/2.htm
22 Jan 2021
Prevalence of liver fibrosis in diabetes suggests need for earlier intervention, study finds
The prevalence of any suspected liver fibrosis in patients with diabetes was 21% in a recent study, leading the authors to call for more aggressive screening in patients with obesity and diabetes.
https://gastroenterology.acponline.org/archives/2021/01/22/3.htm
22 Jan 2021
AASLD offers guidance on reproductive health and liver disease
Menopausal hormone therapy should not be used in women with decompensated liver function, Budd-Chiari syndrome, or hepatocellular adenomas, the American Association for the Study of Liver Diseases (AASLD) said, among other recommendations.
https://gastroenterology.acponline.org/archives/2020/09/25/2.htm
25 Sep 2020