Search results for "Opioid-induced constipation"
Mu-opioid receptor antagonists appear safe, effective for opioid-induced constipation, review finds
Researchers looked at randomized controlled trials of peripheral mu-opioid receptor antagonists (methylnaltrexone, naloxone, naloxegol, alvimopan, axelopran, or naldemedine) and the prescription-strength laxatives lubiprostone or prucalopride.
https://gastroenterology.acponline.org/archives/2018/02/23/2.htm
23 Feb 2018
Drug options available for opioid-induced constipation
Four FDA-approved drugs for opioid-induced constipation form the backbone of treatment, with more options in the research pipeline.
https://gastroenterology.acponline.org/archives/2018/04/27/7.htm
27 Apr 2018
AGA issues guideline on opioid-induced constipation
Opioid-induced constipation differs mechanistically from other forms of the disorder, and its medical management deserves dedicated attention, the American Gastroenterological Association (AGA) said.
https://gastroenterology.acponline.org/archives/2018/10/26/1.htm
26 Oct 2018
Naloxone, naldemedine appear best for opioid-induced constipation after laxatives
A meta-analysis found naloxone to have the highest efficacy and safety of pharmacological therapies for opioid-induced constipation, and previous research has shown it to be cost-effective, study authors said.
https://gastroenterology.acponline.org/archives/2018/05/25/1.htm
25 May 2018
MKSAP quiz: Persistent constipation for 2 years
This month's quiz asks readers to determine the most appropriate treatment for persistent constipation in a 60-year-old woman taking chronic opioid analgesic therapy for reflex sympathetic dystrophy syndrome.
https://gastroenterology.acponline.org/archives/2018/12/28/4.htm
28 Dec 2018