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Machine learning model predicted mortality among malnourished inpatients with IBD

Integrating such models into clinical practice could improve identification of inflammatory bowel disease (IBD) patients at risk for malnutrition and potentially reduce their mortality by prompting earlier intervention, according to the authors of a new study.
https://gastroenterology.acponline.org/archives/2025/02/28/3.htm
28 Feb 2025

GLP-1 receptor agonists negatively impact colonoscopy bowel preparation, review finds

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists were more than twice as likely to experience inadequate bowel preparation for colonoscopy than those not taking the medications, a meta-analysis found.
https://gastroenterology.acponline.org/archives/2025/02/28/2.htm
28 Feb 2025

MASH treatments compared in network meta-analysis

Pegozafermin, cilofexor plus firsocostat, and cilofexor plus selonsertib appear to be the most effective interventions for fibrosis regression and resolution of metabolic dysfunction-associated steatohepatitis (MASH), a systematic review and network meta-analysis found.
https://gastroenterology.acponline.org/archives/2025/02/28/1.htm
28 Feb 2025

ACG releases updated EoE guideline

The clinical guideline on diagnosis and management of eosinophilic esophagitis (EoE) from the American College of Gastroenterology (ACG) replaces recommendations from 2013 and offers advice on which medications to use.
https://gastroenterology.acponline.org/archives/2025/01/24/3.htm
24 Jan 2025

Constipation associated with higher stroke risk

Constipated patients had a 50% higher risk of ischemic stroke than those without constipation, according to a recent meta-analysis.
https://gastroenterology.acponline.org/archives/2025/01/24/2.htm
24 Jan 2025

Peer telehealth intervention increases HCV treatment initiation, six-month viral clearance

Patients in rural areas who used drugs were four times more likely to achieve clearance of hepatitis C virus (HCV) at six months with a peer telehealth treatment intervention than with a peer-assisted referral to local treatment resources, according to randomized trial results.
https://gastroenterology.acponline.org/archives/2025/01/24/1.htm
24 Jan 2025

ED visits for EoE appear to vary by season

Visits to the ED for eosinophilic esophagitis (EoE) among U.S. adults peaked in summer (especially on weekends) and fell in winter, were consistent across all regions, and were unaffected by rural versus urban settings, a study found.
https://gastroenterology.acponline.org/archives/2024/12/20/3.htm
20 Dec 2024

Peer-assisted telemedicine boosts HCV treatment, viral clearance rates

A randomized controlled trial in rural Oregon found that patients with hepatitis C virus (HCV) who used drugs were more likely to start treatment and achieve viral clearance if they received peer-assisted telemedicine versus peer-assisted referral to local clinicians.
https://gastroenterology.acponline.org/archives/2024/12/20/2.htm
20 Dec 2024

CRC rescreening interval may be extended beyond 10 years for low-risk individuals, study suggests

Individuals with negative colonoscopy screening results had a persistently lower risk of colorectal cancer (CRC) incidence and mortality for at least 20 years compared with individuals whose results showed CRC or polyps, according to a cohort study.
https://gastroenterology.acponline.org/archives/2024/12/20/1.htm
20 Dec 2024

Only half of patients with SBP received albumin per guidelines, VA study finds

Use of albumin for spontaneous bacterial peritonitis (SBP) was lower among Black patients than White ones, but it did increase over time from 2008 to 2021, according to a retrospective Veterans Affairs (VA) study.
https://gastroenterology.acponline.org/archives/2024/11/22/3.htm
22 Nov 2024

Risk for herpes zoster complications appears higher with IBD

A retrospective cohort study found that herpes zoster complications occurred in 15.52% of patients with inflammatory bowel disease (IBD) who got the virus versus 12.51% of those without IBD, a statistically significant difference.
https://gastroenterology.acponline.org/archives/2024/11/22/2.htm
22 Nov 2024

Adding factors to FIB-4 improves early identification of patients with risk of HCC

The score, which took into account age, sex, race and ethnicity, body mass index, diabetes status, smoking status, alcohol use, and Fibrosis-4 Index (FIB-4) score, found patients at risk of hepatocellular cancer (HCC) who didn't have viral hepatitis or cirrhosis.
https://gastroenterology.acponline.org/archives/2024/11/22/1.htm
22 Nov 2024

Elimination diets, PPIs most cost-effective for EoE treatment

Elimination diets were the most cost-effective strategy for treatment of eosinophilic esophagitis (EoE) over a five-year period, while proton-pump inhibitors (PPIs) were the most cost-effective first-line drugs, a recent study found.
https://gastroenterology.acponline.org/archives/2024/10/25/3.htm
25 Oct 2024

AI-assisted colonoscopy does not improve detection of advanced neoplasias

While colonoscopies with artificial intelligence (AI) assistance yielded more adenomas compared with conventional colonoscopy, rates of advanced neoplasias per colonoscopy did not differ, a systematic review and meta-analysis found.
https://gastroenterology.acponline.org/archives/2024/10/25/2.htm
25 Oct 2024

Combined FIT, H. pylori testing not linked with lower gastric cancer mortality

Inviting patients to get both Helicobacter pylori stool antigen testing and a fecal immunochemical test (FIT) was associated with lower gastric cancer incidence than FIT alone after adjustment, but no change in related mortality, according to a Taiwanese trial.
https://gastroenterology.acponline.org/archives/2024/10/25/1.htm
25 Oct 2024

Hepatitis D co-infection linked with worse outcomes, higher mortality in hepatitis B

Patients with both hepatitis D and hepatitis B are more than twice as likely to develop hepatocellular carcinoma and decompensation and to die of liver-related causes than those with hepatitis B virus alone, according to a study of Veterans Health Administration data.
https://gastroenterology.acponline.org/archives/2024/09/27/3.htm
27 Sep 2024

Fecal immunochemical tests vary widely in sensitivity, specificity

The test positivity rate among five commonly used fecal immunochemical tests varied from 3.9% to 16.4%, and rates of unevaluable tests ranged from 0.2% to 2.5%. The sensitivity for advanced neoplasia varied from 10.1% to 36.7%, and specificity varied from 85.5% to 96.6%.
https://gastroenterology.acponline.org/archives/2024/09/27/2.htm
27 Sep 2024

ACG updates guideline on H. pylori treatment

Among other recommendations, the American College of Gastroenterology (ACG) said that 14 days of bismuth quadruple therapy is the preferred regimen for treatment-naive patients with Helicobacter pylori infection when antibiotic susceptibility is unknown.
https://gastroenterology.acponline.org/archives/2024/09/27/1.htm
27 Sep 2024

GLP-1 receptor agonists associated with retention of gastric contents during endoscopy

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists did not have any increase in upper endoscopy adverse events, a review found, leading the authors to suggest that longer fasting time before procedures would be sufficient to avoid the risks.
https://gastroenterology.acponline.org/archives/2024/08/23/3.htm
23 Aug 2024

FIB-4 may identify patients at risk for MASLD despite normal aminotransferase levels

More than two-thirds of primary care patients who had high or indeterminate risk for metabolic dysfunction-associated steatotic liver disease (MASLD) based on the fibrosis-4 (FIB-4) score had aminotransferase levels within normal limits.
https://gastroenterology.acponline.org/archives/2024/08/23/2.htm
23 Aug 2024

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