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Mu-opioid receptor antagonists appear safe, effective for opioid-induced constipation, review finds

Researchers looked at randomized controlled trials of peripheral mu-opioid receptor antagonists (methylnaltrexone, naloxone, naloxegol, alvimopan, axelopran, or naldemedine) and the prescription-strength laxatives lubiprostone or prucalopride.
https://gastroenterology.acponline.org/archives/2018/02/23/2.htm
23 Feb 2018

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