Search results for "Highlights"
Systematic review highlights need to test IBS patients for celiac disease
Of 7,209 patients diagnosed with irritable bowel disease (IBS), 6% were seropositive for celiac disease, according to a review of studies conducted in countries where such testing was not routine.
https://gastroenterology.acponline.org/archives/2025/06/27/2.htm
27 Jun 2025
Spotlight on The Liver Meeting
Highlights from the American Association for the Study of Liver Diseases' annual meeting, held virtually this past weekend, included insights on COVID-19 and the liver and a conversation with the winners of the Nobel Prize in Physiology or Medicine 2020, who discovered hepatitis C virus.
https://gastroenterology.acponline.org/archives/2020/11/20/5.htm
20 Nov 2020
Spotlight on Digestive Disease Week
Highlights from the conference, held this past week in San Diego, included new research and clinical tips on stopping Barrett's esophagus surveillance, diet and environmental risk factors in patients with inflammatory bowel disease, and new research on proton-pump inhibitors.
https://gastroenterology.acponline.org/archives/2019/05/24/5.htm
24 May 2019
Study assesses remission, complication rates with vedolizumab in early, late Crohn's
Patients with Crohn's disease who started vedolizumab within two years of diagnosis were significantly more likely to reach clinical and endoscopic remission than those who had been diagnosed more than two years earlier and already received anti-tumor necrosis factor agents, a manufacturer-supported trial found.
https://gastroenterology.acponline.org/archives/2025/11/21/3.htm
21 Nov 2025
Opioids after IBD hospitalization tied to worse outcomes
Patients with inflammatory bowel disease (IBD) who filled an opioid prescription within seven days of a hospital or ED visit were more likely to come back to the hospital, to receive a corticosteroid prescription, or to have an escalation of medical therapy.
https://gastroenterology.acponline.org/archives/2025/11/21/2.htm
21 Nov 2025
Anti-interleukins, JAK inhibitors linked with lower infection risk in ulcerative colitis
Both anti-interleukins and Janus kinase (JAK) inhibitors were associated with a lower risk of serious infections than tumor necrosis factor antagonists, according to a retrospective study of more than 9,000 patients with ulcerative colitis.
https://gastroenterology.acponline.org/archives/2025/11/21/1.htm
21 Nov 2025
Elevated uric acid linked with increased risk of MAFLD, review shows
Patients with the highest serum uric acid levels were 1.9 times more likely to develop metabolic dysfunction-associated fatty liver disease (MAFLD) than those with the lowest levels, a meta-analysis of 61 studies with more than two million participants found.
https://gastroenterology.acponline.org/archives/2025/10/24/3.htm
24 Oct 2025
Vonoprazan improved nocturnal reflux symptoms in nonerosive disease, industry trial found
Vonoprazan had a rapid effect on nighttime heartburn symptoms that was sustained through 24 weeks, a phase 3 placebo-controlled trial found.
https://gastroenterology.acponline.org/archives/2025/10/24/2.htm
24 Oct 2025
AGA releases best practice advice on cirrhosis
The guidance from the American Gastroenterological Association (AGA) covered management of ascites, hepatic hydrothorax, volume overload, and hyponatremia in and out of the hospital.
https://gastroenterology.acponline.org/archives/2025/10/24/1.htm
24 Oct 2025
Antibiotic prophylaxis appears to reduce risk of infectious complications of ERCP
However, antibiotic prophylaxis in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) was not associated with improvements in mortality or pancreatitis rates, a review of 11 randomized trials found.
https://gastroenterology.acponline.org/archives/2025/09/26/3.htm
26 Sep 2025
Daily aspirin was associated with reduced colorectal cancer recurrence in patients with genetic mutations
Among patients with alterations in PI3K pathway genes and a history of colorectal cancer, the estimated three-year cumulative recurrence rate was 7.7% in those who took daily low-dose aspirin compared with 14.1% in controls, a Scandinavian trial found.
https://gastroenterology.acponline.org/archives/2025/09/26/2.htm
26 Sep 2025
Global group offers recommendations on IBD at all stages of pregnancy
A global consensus statement on the management of pregnancy in inflammatory bowel disease (IBD) provides advice on how to manage medications and reduce risk of complications, among other topics.
https://gastroenterology.acponline.org/archives/2025/09/26/1.htm
26 Sep 2025
Shorter treatment possible for HCV, phase 2 study finds
Four weeks of daily glecaprevir and pibrentasvir resulted in sustained virologic response at 12 weeks in 84% of patients with early hepatitis C virus (HCV) infection, a study found.
https://gastroenterology.acponline.org/archives/2025/08/22/3.htm
22 Aug 2025
Cancer, decompensation more likely in men with cirrhosis than women
Men with cirrhosis had more than double the risk of hepatocellular carcinoma, a 63% higher risk of liver transplant, and a 16% higher risk of decompensated cirrhosis than women with the disease, and the differences were greatest in those with alcohol-related disease, a study found.
https://gastroenterology.acponline.org/archives/2025/08/22/2.htm
22 Aug 2025
FMT appears safe, effective for recurrent C. diff in immunocompromised patients
Patients with mild to moderate immunocompromise and recurrent Clostridioides difficile infection had similar outcomes to immunocompetent patients after fecal microbiota transplantation (FMT), according to a systematic review and meta-analysis.
https://gastroenterology.acponline.org/archives/2025/08/22/1.htm
22 Aug 2025
Regular CBD use linked with liver enzyme elevations, FDA trial finds
More than 5% of study participants randomized to cannabidiol (CBD) twice daily for 28 days had an alanine aminotransferase or aspartate aminotransferase level of at least three times normal, suggesting that moderate CBD doses may carry hepatic risks.
https://gastroenterology.acponline.org/archives/2025/07/25/3.htm
25 Jul 2025
Several drug classes reviewed, found unlikely to trigger microscopic colitis
Microscopic colitis rates were not elevated in patients taking NSAIDs, proton-pump inhibitors, statins, angiotensin-converting enzyme inhibitors, or angiotensin-receptor blockers.
https://gastroenterology.acponline.org/archives/2025/07/25/2.htm
25 Jul 2025
Empiric treatments for Helicobacter pylori compared
Concomitant and bismuth quadruple therapies had the highest eradication rates for initial treatment, while bismuth quadruple therapy was most successful as a salvage regimen, a retrospective cohort study in the U.S. found.
https://gastroenterology.acponline.org/archives/2025/07/25/1.htm
25 Jul 2025
Screening men with HIV for anal cancer most cost-effective when initiated at age 35
In men with HIV infection who have sex with men, incremental cost-effectiveness ratios ranged from $87,731 for quadrennial cytology to $350,100 for annual cytology beginning at age 35 years, a microsimulation model found.
https://gastroenterology.acponline.org/archives/2025/06/27/3.htm
27 Jun 2025
GLP-1 RAs associated with increased risk of gallstones, reflux, meta-analysis finds
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) did not significantly increase the risk of pancreatitis, cholecystitis, intestinal obstruction, or other serious gastrointestinal or biliary events.
https://gastroenterology.acponline.org/archives/2025/06/27/1.htm
27 Jun 2025