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Lowering colorectal cancer screening age from 50 to 45 years appears cost-effective

Initiating screening at age 45 years would require an additional 10 million colonoscopies, which could potentially provide greater benefit if used instead to increase screening rates in older patients, authors of the modeling study said.
https://gastroenterology.acponline.org/archives/2019/04/26/1.htm
26 Apr 2019

Daily aspirin may reduce risk of hepatitis-related liver cancer

A Taiwanese nationwide cohort study of more than 10,000 patients with chronic hepatitis B showed a statistically significant 29% risk reduction for hepatocellular carcinoma in patients who received daily aspirin compared with matched controls.
https://gastroenterology.acponline.org/archives/2019/03/22/1.htm
22 Mar 2019

Boxed warning added to liver disease drug

The drug has been incorrectly dosed daily instead of weekly in patients with moderate to severe primary biliary cholangitis, which increases the risk of serious liver injury, the FDA said.
https://gastroenterology.acponline.org/archives/2018/02/23/7.htm
23 Feb 2018

USPSTF continues to recommend against screening for pancreatic cancer

There is no evidence that screening for pancreatic cancer or treating screen-detected disease improves disease-specific morbidity or all-cause mortality in average-risk adults with no symptoms, the U.S. Preventive Services Task Force (USPSTF) concluded.
https://gastroenterology.acponline.org/archives/2019/08/23/1.htm
23 Aug 2019

Screening for Lynch syndrome less effective at older ages, study finds

Lynch syndrome is rare after age 80 years, making the efficiency of universal screening very low, so stopping reflex screening in this age group may be reasonable, particularly in resource-limited settings, the study authors said.
https://gastroenterology.acponline.org/archives/2019/06/28/1.htm
28 Jun 2019

Patients may not always want to stop low-value colorectal cancer screening

Veterans at one health system were asked to rate the reasonableness of using age and risk calculators in decisions about screening cessation.
https://gastroenterology.acponline.org/archives/2018/12/28/1.htm
28 Dec 2018

AGA issues guideline on opioid-induced constipation

Opioid-induced constipation differs mechanistically from other forms of the disorder, and its medical management deserves dedicated attention, the American Gastroenterological Association (AGA) said.
https://gastroenterology.acponline.org/archives/2018/10/26/1.htm
26 Oct 2018

ACIP revises recommendations on hepatitis A vaccination

For postexposure prophylaxis, the hepatitis A vaccine is now preferred to immune globulin for all adults, including those older than 40 years of age, the Advisory Committee on Immunization Practices (ACIP) said.
https://gastroenterology.acponline.org/archives/2018/11/27/1.htm
27 Nov 2018

8 weeks of ledipasvir/sofosbuvir may be effective for genotype 1 hepatitis C

The therapy should be considered in patients with genotype 1 infection who are treatment-naive, do not have cirrhosis, and have a pretreatment viral load below 6,000,000 IU/mL, a study found.
https://gastroenterology.acponline.org/archives/2017/03/24/2.htm
24 Mar 2017

Scores to predict outcomes of upper GI bleeding compared

Researchers calculated three pre-endoscopy scores—admission Rockall, AIMS65, and Glasgow Blatchford—and two postendoscopy scores—full Rockall and PNED.
https://gastroenterology.acponline.org/archives/2017/01/27/4.htm
27 Jan 2017

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