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Systematic review highlights need to test IBS patients for celiac disease

Of 7,209 patients diagnosed with irritable bowel disease (IBS), 6% were seropositive for celiac disease, according to a review of studies conducted in countries where such testing was not routine.
https://gastroenterology.acponline.org/archives/2025/06/27/2.htm
27 Jun 2025

Spotlight on The Liver Meeting

Highlights from the American Association for the Study of Liver Diseases' annual meeting, held virtually this past weekend, included insights on COVID-19 and the liver and a conversation with the winners of the Nobel Prize in Physiology or Medicine 2020, who discovered hepatitis C virus.
https://gastroenterology.acponline.org/archives/2020/11/20/5.htm
20 Nov 2020

Spotlight on Digestive Disease Week

Highlights from the conference, held this past week in San Diego, included new research and clinical tips on stopping Barrett's esophagus surveillance, diet and environmental risk factors in patients with inflammatory bowel disease, and new research on proton-pump inhibitors.
https://gastroenterology.acponline.org/archives/2019/05/24/5.htm
24 May 2019

Screening men with HIV for anal cancer most cost-effective when initiated at age 35

In men with HIV infection who have sex with men, incremental cost-effectiveness ratios ranged from $87,731 for quadrennial cytology to $350,100 for annual cytology beginning at age 35 years, a microsimulation model found.
https://gastroenterology.acponline.org/archives/2025/06/27/3.htm
27 Jun 2025

GLP-1 RAs associated with increased risk of gallstones, reflux, meta-analysis finds

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) did not significantly increase the risk of pancreatitis, cholecystitis, intestinal obstruction, or other serious gastrointestinal or biliary events.
https://gastroenterology.acponline.org/archives/2025/06/27/1.htm
27 Jun 2025

Incidentally detected gallbladder polyps often get unneeded follow-up

Over more than two years of follow-up, gallbladder polyps increased in size in 26.0% of patients, and although cholecystectomy and follow-up imaging were commonly performed, no malignant polyps were detected, a retrospective study found.
https://gastroenterology.acponline.org/archives/2025/05/23/3.htm
23 May 2025

Nuts, seeds did not trigger diverticulitis in women, study finds

Although intake of peanuts, nuts, and seeds or fresh fruits with edible seeds was not associated with incident diverticulitis, women who reported healthier diets had lower risk of the condition, a cohort study found.
https://gastroenterology.acponline.org/archives/2025/05/23/2.htm
23 May 2025

Review suggests infliximab superior to cyclosporine for acute severe ulcerative colitis

Infliximab was superior to cyclosporine for reducing the risk of colectomy in patients with acute severe ulcerative colitis, although infection risk was higher with infliximab, a meta-analysis of 44 studies found.
https://gastroenterology.acponline.org/archives/2025/05/23/1.htm
23 May 2025

Study supports bariatric surgery in patients with obesity and cirrhosis

An economic evaluation of Veterans Health Administration data found that bariatric surgery was cost-effective among patients with cirrhosis at a willingness-to-pay threshold of $100,000 per quality-adjusted life-year.
https://gastroenterology.acponline.org/archives/2025/04/25/3.htm
25 Apr 2025

Patient navigation improves colonoscopy completion at 1 year, study finds

Rates of follow-up colonoscopy in a U.S. study were higher in patients assigned to receive telephone-based navigation after an abnormal stool test versus usual care.
https://gastroenterology.acponline.org/archives/2025/04/25/2.htm
25 Apr 2025

Universal HDV screening in patients with HBV appears cost-effective

Compared with status quo screening rates, universal hepatitis D virus (HDV) testing of adults with chronic hepatitis B virus (HBV) infection could avert 100 HDV-related deaths, an additional 30 cases of cirrhosis, and 50 cases of hepatocellular carcinoma per 100,000 people screened, according to a modeling study.
https://gastroenterology.acponline.org/archives/2025/04/25/1.htm
25 Apr 2025

Mailed FIT, patient navigation increased CRC screening in rural Medicaid enrollees

A program that mailed fecal immunochemical tests (FITs) to Medicaid enrollees and implemented patient navigation to colonoscopies after an abnormal result increased colorectal cancer screening participation at six months by 7.3 percentage points compared with usual care, according to a multicenter trial.
https://gastroenterology.acponline.org/archives/2025/03/28/3.htm
28 Mar 2025

AKI in cirrhosis can still show response to albumin after 24 hours, study finds

After 48 hours of albumin treatment, between 30% and 54% of patients with cirrhosis and acute kidney injury (AKI) had responded (depending on the definition of response). At 24 hours, only 25% to 38% had shown a response, a prospective study found.
https://gastroenterology.acponline.org/archives/2025/03/28/2.htm
28 Mar 2025

First-of-kind guideline outlines surveillance of premalignant gastric conditions

Goals of the new guideline from the American College of Gastroenterology include reducing gastric cancer incidence, improving the detection of early-stage disease, and significantly increasing five-year survival rates.
https://gastroenterology.acponline.org/archives/2025/03/28/1.htm
28 Mar 2025

In the Clinic: Hemochromatosis

An In the Clinic article provided an overview of hemochromatosis, an inheritable condition that mainly affects White populations of European descent.
https://gastroenterology.acponline.org/archives/2025/02/28/7.htm
28 Feb 2025

Machine learning model predicted mortality among malnourished inpatients with IBD

Integrating such models into clinical practice could improve identification of inflammatory bowel disease (IBD) patients at risk for malnutrition and potentially reduce their mortality by prompting earlier intervention, according to the authors of a new study.
https://gastroenterology.acponline.org/archives/2025/02/28/3.htm
28 Feb 2025

GLP-1 receptor agonists negatively impact colonoscopy bowel preparation, review finds

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists were more than twice as likely to experience inadequate bowel preparation for colonoscopy than those not taking the medications, a meta-analysis found.
https://gastroenterology.acponline.org/archives/2025/02/28/2.htm
28 Feb 2025

MASH treatments compared in network meta-analysis

Pegozafermin, cilofexor plus firsocostat, and cilofexor plus selonsertib appear to be the most effective interventions for fibrosis regression and resolution of metabolic dysfunction-associated steatohepatitis (MASH), a systematic review and network meta-analysis found.
https://gastroenterology.acponline.org/archives/2025/02/28/1.htm
28 Feb 2025

ACG releases updated EoE guideline

The clinical guideline on diagnosis and management of eosinophilic esophagitis (EoE) from the American College of Gastroenterology (ACG) replaces recommendations from 2013 and offers advice on which medications to use.
https://gastroenterology.acponline.org/archives/2025/01/24/3.htm
24 Jan 2025

Constipation associated with higher stroke risk

Constipated patients had a 50% higher risk of ischemic stroke than those without constipation, according to a recent meta-analysis.
https://gastroenterology.acponline.org/archives/2025/01/24/2.htm
24 Jan 2025

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