Search results for "Highlights"
Amoxicillin-clavulanate appears safe, effective for diverticulitis in outpatients
A retrospective cohort study compared amoxicillin-clavulanate with metronidazole-fluoroquinolone and found no differences in outcomes including risks for inpatient admission or surgery, while Clostridioides difficile risk appeared higher in older patients on the latter regimen.
https://gastroenterology.acponline.org/archives/2021/02/26/2.htm
26 Feb 2021
Tenofovir alafenamide may safely replace tenofovir disoproxil fumarate in patients with drug-resistant HBV, trial finds
An industry-funded randomized trial found that tenofovir alafenamide could be substituted for tenofovir disoproxil fumarate in patients with multidrug-resistant hepatitis B virus (HBV) for improved bone and renal safety without a loss of efficacy; however, the former drug was associated with greater increases in body weight and cholesterol levels.
https://gastroenterology.acponline.org/archives/2021/05/28/4.htm
28 May 2021
Three rounds of FIT had higher CRC detection rates than one sigmoidoscopy, study finds
Participation was higher and more colorectal cancer (CRC) and advanced adenomas were detected with repeated fecal immunochemical testing (FIT) compared to sigmoidoscopy, although the risks of perforation and bleeding were comparable.
https://gastroenterology.acponline.org/archives/2020/12/18/3.htm
18 Dec 2020
Urgent endoscopy did not improve outcomes from acute upper GI bleeds
Thirty-day mortality was slightly lower among high-risk patients who underwent endoscopy for an acute upper GI bleed within 24 hours of a consult instead of within six hours, although the difference was not statistically significant.
https://gastroenterology.acponline.org/archives/2020/04/24/3.htm
24 Apr 2020
Prevalence of liver fibrosis in diabetes suggests need for earlier intervention, study finds
The prevalence of any suspected liver fibrosis in patients with diabetes was 21% in a recent study, leading the authors to call for more aggressive screening in patients with obesity and diabetes.
https://gastroenterology.acponline.org/archives/2021/01/22/3.htm
22 Jan 2021
GI symptoms associated with better outcomes from COVID-19, new two-part study finds
SARS-CoV-2 was commonly present in the gastrointestinal tract but didn't cause inflammation there, according to a recent analysis of intestinal biopsy tissues from patients with COVID-19.
https://gastroenterology.acponline.org/archives/2021/03/26/2.htm
26 Mar 2021
PPIs not associated with mortality risk for most causes, study finds
While patients who took proton-pump inhibitors (PPIs) had significantly higher risks of all-cause mortality and mortality due to cancer, cardiovascular diseases, respiratory diseases, and digestive diseases, lag times of up to six years attenuated these associations so they were no longer statistically significant.
https://gastroenterology.acponline.org/archives/2022/07/22/1.htm
22 Jul 2022
Education for patients reduced upper GI endoscopies for uninvestigated dyspepsia
To reduce overuse, a Dutch trial provided a self-managed, web-based educational intervention containing information on gastric function, dyspepsia, and upper GI tract endoscopy to some patients referred for the procedure by their primary care clinicians.
https://gastroenterology.acponline.org/archives/2021/05/28/3.htm
28 May 2021
Patients with mild acute diverticulitis can be safely treated without antibiotics in outpatient setting
Patients who presented to an ED and were randomized to receive only anti-inflammatory and symptomatic treatment had similar rates of hospitalization, return to the ED, and pain control as those who received the usual antibiotic treatment, a Spanish trial found.
https://gastroenterology.acponline.org/archives/2021/11/19/2.htm
19 Nov 2021
Mailed FIT screening for CRC effective, cost-effective in safety-net population
Patients at a federally qualified health center system in Central Texas who were not up to date on colorectal cancer (CRC) screening were mailed a packet containing an introductory letter, a fecal immunochemical test (FIT), easy-to-read instructions, and a postage-paid lab mailer.
https://gastroenterology.acponline.org/archives/2021/05/28/2.htm
28 May 2021