Search results for "Highlights"
EoE patients with high BMI may be less likely to respond to topical corticosteroids
A retrospective cohort study of patients with eosinophilic esophagitis (EoE) found that each 1-point increase in body mass index (BMI) was associated with a 7% decrease in odds of histologic response to topical corticosteroids and that patients with obesity had about 40% odds of responding compared to those without.
https://gastroenterology.acponline.org/archives/2022/12/23/2.htm
23 Dec 2022
Review finds only two efficacious medications to treat gastroparesis
Clebopride ranked first for efficacy, followed by domperidone, and no other drug was superior to placebo for improving symptoms of gastroparesis, according to a recent meta-analysis.
https://gastroenterology.acponline.org/archives/2023/01/27/2.htm
27 Jan 2023
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
Bariatric surgery associated with lower risk of obesity-related cancer
An observational study found significant reductions in a composite outcome of 13 cancers and related mortality in patients with a body mass index of 35 kg/m2 or greater who had bariatric surgery in 2004 to 2017, compared to those who did not undergo surgery for their obesity.
https://gastroenterology.acponline.org/archives/2022/06/24/2.htm
24 Jun 2022
Patient beliefs associated with successful antibiotic treatment of appendicitis
A secondary analysis of a randomized clinical trial found lower risk for appendectomy and higher likelihood of 30-day resolution of signs and symptoms among those who believed that antibiotics could be completely successful versus those who thought they would be unsuccessful or were unsure.
https://gastroenterology.acponline.org/archives/2022/10/28/2.htm
28 Oct 2022
Societies issue joint statement on metabolic, bariatric surgery
The American Society for Metabolic and Bariatric Surgery and the International Federation for the Surgery of Obesity and Metabolic Disorders support surgery for patients with a body mass index of 35 kg/m2 or higher regardless of comorbid conditions, among other guidance.
https://gastroenterology.acponline.org/archives/2022/11/18/3.htm
18 Nov 2022
Heart failure risk increased in patients with NAFLD, meta-analysis finds
Nonalcoholic fatty liver disease (NAFLD) was associated with a 50% increased risk of new-onset heart failure, independent of age, sex, diabetes, hypertension, and other common cardiovascular risk factors, according to an international meta-analysis.
https://gastroenterology.acponline.org/archives/2022/08/26/2.htm
26 Aug 2022
AGA issues guidance on drug treatment for patients with IBS
Two new clinical practice guidelines from the American Gastroenterological Association (AGA) provide recommendations on the use of medications to treat irritable bowel syndrome (IBS) with constipation and IBS with diarrhea.
https://gastroenterology.acponline.org/archives/2022/06/24/1.htm
24 Jun 2022
Review examines drugs, lifestyle treatments for NAFLD
The umbrella review included 27 meta-analyses of randomized controlled trials examining the effectiveness of pharmacological interventions and lifestyle modifications, including diet and exercise, for patients with nonalcoholic fatty liver disease (NAFLD).
https://gastroenterology.acponline.org/archives/2022/05/27/2.htm
27 May 2022
IV iron regimens compared for serum phosphate effects in patients with IBD
Ferric carboxymaltose and ferric derisomaltose worked well to resolve anemia from inflammatory bowel disease (IBD), but the former was associated with low serum phosphate levels, according to an industry-funded trial.
https://gastroenterology.acponline.org/archives/2022/09/23/2.htm
23 Sep 2022