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Study supports bariatric surgery in patients with obesity and cirrhosis

An economic evaluation of Veterans Health Administration data found that bariatric surgery was cost-effective among patients with cirrhosis at a willingness-to-pay threshold of $100,000 per quality-adjusted life-year.
https://gastroenterology.acponline.org/archives/2025/04/25/3.htm
25 Apr 2025

Patient navigation improves colonoscopy completion at 1 year, study finds

Rates of follow-up colonoscopy in a U.S. study were higher in patients assigned to receive telephone-based navigation after an abnormal stool test versus usual care.
https://gastroenterology.acponline.org/archives/2025/04/25/2.htm
25 Apr 2025

Universal HDV screening in patients with HBV appears cost-effective

Compared with status quo screening rates, universal hepatitis D virus (HDV) testing of adults with chronic hepatitis B virus (HBV) infection could avert 100 HDV-related deaths, an additional 30 cases of cirrhosis, and 50 cases of hepatocellular carcinoma per 100,000 people screened, according to a modeling study.
https://gastroenterology.acponline.org/archives/2025/04/25/1.htm
25 Apr 2025

Mailed FIT, patient navigation increased CRC screening in rural Medicaid enrollees

A program that mailed fecal immunochemical tests (FITs) to Medicaid enrollees and implemented patient navigation to colonoscopies after an abnormal result increased colorectal cancer screening participation at six months by 7.3 percentage points compared with usual care, according to a multicenter trial.
https://gastroenterology.acponline.org/archives/2025/03/28/3.htm
28 Mar 2025

AKI in cirrhosis can still show response to albumin after 24 hours, study finds

After 48 hours of albumin treatment, between 30% and 54% of patients with cirrhosis and acute kidney injury (AKI) had responded (depending on the definition of response). At 24 hours, only 25% to 38% had shown a response, a prospective study found.
https://gastroenterology.acponline.org/archives/2025/03/28/2.htm
28 Mar 2025

First-of-kind guideline outlines surveillance of premalignant gastric conditions

Goals of the new guideline from the American College of Gastroenterology include reducing gastric cancer incidence, improving the detection of early-stage disease, and significantly increasing five-year survival rates.
https://gastroenterology.acponline.org/archives/2025/03/28/1.htm
28 Mar 2025

Machine learning model predicted mortality among malnourished inpatients with IBD

Integrating such models into clinical practice could improve identification of inflammatory bowel disease (IBD) patients at risk for malnutrition and potentially reduce their mortality by prompting earlier intervention, according to the authors of a new study.
https://gastroenterology.acponline.org/archives/2025/02/28/3.htm
28 Feb 2025

GLP-1 receptor agonists negatively impact colonoscopy bowel preparation, review finds

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists were more than twice as likely to experience inadequate bowel preparation for colonoscopy than those not taking the medications, a meta-analysis found.
https://gastroenterology.acponline.org/archives/2025/02/28/2.htm
28 Feb 2025

MASH treatments compared in network meta-analysis

Pegozafermin, cilofexor plus firsocostat, and cilofexor plus selonsertib appear to be the most effective interventions for fibrosis regression and resolution of metabolic dysfunction-associated steatohepatitis (MASH), a systematic review and network meta-analysis found.
https://gastroenterology.acponline.org/archives/2025/02/28/1.htm
28 Feb 2025

ACG releases updated EoE guideline

The clinical guideline on diagnosis and management of eosinophilic esophagitis (EoE) from the American College of Gastroenterology (ACG) replaces recommendations from 2013 and offers advice on which medications to use.
https://gastroenterology.acponline.org/archives/2025/01/24/3.htm
24 Jan 2025

Constipation associated with higher stroke risk

Constipated patients had a 50% higher risk of ischemic stroke than those without constipation, according to a recent meta-analysis.
https://gastroenterology.acponline.org/archives/2025/01/24/2.htm
24 Jan 2025

Peer telehealth intervention increases HCV treatment initiation, six-month viral clearance

Patients in rural areas who used drugs were four times more likely to achieve clearance of hepatitis C virus (HCV) at six months with a peer telehealth treatment intervention than with a peer-assisted referral to local treatment resources, according to randomized trial results.
https://gastroenterology.acponline.org/archives/2025/01/24/1.htm
24 Jan 2025

ED visits for EoE appear to vary by season

Visits to the ED for eosinophilic esophagitis (EoE) among U.S. adults peaked in summer (especially on weekends) and fell in winter, were consistent across all regions, and were unaffected by rural versus urban settings, a study found.
https://gastroenterology.acponline.org/archives/2024/12/20/3.htm
20 Dec 2024

Peer-assisted telemedicine boosts HCV treatment, viral clearance rates

A randomized controlled trial in rural Oregon found that patients with hepatitis C virus (HCV) who used drugs were more likely to start treatment and achieve viral clearance if they received peer-assisted telemedicine versus peer-assisted referral to local clinicians.
https://gastroenterology.acponline.org/archives/2024/12/20/2.htm
20 Dec 2024

CRC rescreening interval may be extended beyond 10 years for low-risk individuals, study suggests

Individuals with negative colonoscopy screening results had a persistently lower risk of colorectal cancer (CRC) incidence and mortality for at least 20 years compared with individuals whose results showed CRC or polyps, according to a cohort study.
https://gastroenterology.acponline.org/archives/2024/12/20/1.htm
20 Dec 2024

Only half of patients with SBP received albumin per guidelines, VA study finds

Use of albumin for spontaneous bacterial peritonitis (SBP) was lower among Black patients than White ones, but it did increase over time from 2008 to 2021, according to a retrospective Veterans Affairs (VA) study.
https://gastroenterology.acponline.org/archives/2024/11/22/3.htm
22 Nov 2024

Risk for herpes zoster complications appears higher with IBD

A retrospective cohort study found that herpes zoster complications occurred in 15.52% of patients with inflammatory bowel disease (IBD) who got the virus versus 12.51% of those without IBD, a statistically significant difference.
https://gastroenterology.acponline.org/archives/2024/11/22/2.htm
22 Nov 2024

Adding factors to FIB-4 improves early identification of patients with risk of HCC

The score, which took into account age, sex, race and ethnicity, body mass index, diabetes status, smoking status, alcohol use, and Fibrosis-4 Index (FIB-4) score, found patients at risk of hepatocellular cancer (HCC) who didn't have viral hepatitis or cirrhosis.
https://gastroenterology.acponline.org/archives/2024/11/22/1.htm
22 Nov 2024

Elimination diets, PPIs most cost-effective for EoE treatment

Elimination diets were the most cost-effective strategy for treatment of eosinophilic esophagitis (EoE) over a five-year period, while proton-pump inhibitors (PPIs) were the most cost-effective first-line drugs, a recent study found.
https://gastroenterology.acponline.org/archives/2024/10/25/3.htm
25 Oct 2024

AI-assisted colonoscopy does not improve detection of advanced neoplasias

While colonoscopies with artificial intelligence (AI) assistance yielded more adenomas compared with conventional colonoscopy, rates of advanced neoplasias per colonoscopy did not differ, a systematic review and meta-analysis found.
https://gastroenterology.acponline.org/archives/2024/10/25/2.htm
25 Oct 2024

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