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In the Clinic, 2023 summary highlight gastroenterology topics

Colorectal cancer screening was the focus of the latest In the Clinic article, while an article in a supplement to Annals reviewed clinically important developments in gastroenterology and hepatology in 2023.
https://gastroenterology.acponline.org/archives/2024/04/26/5.htm
26 Apr 2024

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ACP Gastroenterology Monthly delivers a monthly summary of news in gastroenterology and hepatology, including the latest research, clinical guidelines, and FDA drug actions.
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Fecal immunochemical tests vary widely in sensitivity, specificity

The test positivity rate among five commonly used fecal immunochemical tests varied from 3.9% to 16.4%, and rates of unevaluable tests ranged from 0.2% to 2.5%. The sensitivity for advanced neoplasia varied from 10.1% to 36.7%, and specificity varied from 85.5% to 96.6%.
https://gastroenterology.acponline.org/archives/2024/09/27/2.htm
27 Sep 2024

Hepatitis D co-infection linked with worse outcomes, higher mortality in hepatitis B

Patients with both hepatitis D and hepatitis B are more than twice as likely to develop hepatocellular carcinoma and decompensation and to die of liver-related causes than those with hepatitis B virus alone, according to a study of Veterans Health Administration data.
https://gastroenterology.acponline.org/archives/2024/09/27/3.htm
27 Sep 2024

ACG updates guideline on H. pylori treatment

Among other recommendations, the American College of Gastroenterology (ACG) said that 14 days of bismuth quadruple therapy is the preferred regimen for treatment-naive patients with Helicobacter pylori infection when antibiotic susceptibility is unknown.
https://gastroenterology.acponline.org/archives/2024/09/27/1.htm
27 Sep 2024

FIB-4 may identify patients at risk for MASLD despite normal aminotransferase levels

More than two-thirds of primary care patients who had high or indeterminate risk for metabolic dysfunction-associated steatotic liver disease (MASLD) based on the fibrosis-4 (FIB-4) score had aminotransferase levels within normal limits.
https://gastroenterology.acponline.org/archives/2024/08/23/2.htm
23 Aug 2024

GLP-1 receptor agonists associated with retention of gastric contents during endoscopy

Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists did not have any increase in upper endoscopy adverse events, a review found, leading the authors to suggest that longer fasting time before procedures would be sufficient to avoid the risks.
https://gastroenterology.acponline.org/archives/2024/08/23/3.htm
23 Aug 2024

Clinical practice update advises on management of cyclic vomiting syndrome

A basic workup for episodic vomiting should include bloodwork and urinalysis, and management of cyclic vomiting syndrome often entails multiple abortive medications, the American Gastroenterological Association said.
https://gastroenterology.acponline.org/archives/2024/07/26/3.htm
26 Jul 2024

Diagnostic delays in pancreatic cancer relatively common, likely avoidable, study suggests

Thirty-eight percent of patients with pancreatic cancer experienced a diagnostic delay of at least 60 days, with lack of recognition of objective weight loss as the most common cause, a Veterans Affairs study showed.
https://gastroenterology.acponline.org/archives/2024/08/23/1.htm
23 Aug 2024

Early vs. late paracentesis associated with better outcomes in hospitalized cirrhosis patients

Patients hospitalized with cirrhosis and ascites who received diagnostic paracentesis within 12 to 24 hours of admission had lower rates of in-hospital mortality and acute kidney injury and shorter length of stay than those who received it later, a meta-analysis found.
https://gastroenterology.acponline.org/archives/2024/07/26/2.htm
26 Jul 2024

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