Search results for "Clostridium difficile infection"
Spotlight on fecal microbiota transplantation
Two recent studies focused on fecal microbiota transplantation for recurrent Clostridium difficile infection, while a third examined the utility of anaerobic preparations in patients with mild to moderately active ulcerative colitis.
https://gastroenterology.acponline.org/archives/2019/01/25/5.htm
25 Jan 2019
Fecal transplants by pill noninferior to colonoscopy delivery
The primary outcome of the unblinded, randomized trial was the proportion of patients without recurrent Clostridium difficile infection 12 weeks after fecal transplant.
https://gastroenterology.acponline.org/archives/2017/12/22/1.htm
22 Dec 2017
Fidaxomicin has higher cure rate for C. difficile than other drug options, meta-analysis finds
The study authors concluded that fidaxomicin could be considered as a first-line therapy for Clostridium difficile infection and that metronidazole should not be recommended.
https://gastroenterology.acponline.org/archives/2018/07/27/2.htm
27 Jul 2018
Updated guidelines for C. diff infection address fecal transplant, laboratory testing
The guidelines recommend laboratory testing for C. diff only in patients with new-onset, unexplained diarrhea, defined as at least three unformed stools in 24 hours, among other guidance.
https://gastroenterology.acponline.org/archives/2018/02/23/1.htm
23 Feb 2018
Spotlight on gastric acid suppressants
Use of gastric acid suppressants was linked with increased risk of recurrent Clostridium difficile infection and of first-time ischemic stroke in recent research.
https://gastroenterology.acponline.org/archives/2017/04/28/5.htm
28 Apr 2017
MKSAP quiz: Long-term management of GERD
This month's quiz asks readers to determine the next step in management for a 75-year-old woman with longstanding gastroesophageal reflux disease (GERD) and a new diagnosis of osteopenia.
https://gastroenterology.acponline.org/archives/2019/04/26/4.htm
26 Apr 2019
PPI prophylaxis didn't affect 90-day mortality rates among ICU patients
Gastrointestinal bleeds were less common among at-risk ICU patients who received IV pantoprazole instead of placebo, but rates of clinically important events were similar overall.
https://gastroenterology.acponline.org/archives/2018/10/26/2.htm
26 Oct 2018
High inpatient occupancy levels associated with lower risk of hospital-acquired C. diff
Researchers analyzed administrative data from 2008 to 2012 among Medicare recipients with a discharge diagnosis of acute myocardial infarction, heart failure, or pneumonia at 327 California hospitals.
https://gastroenterology.acponline.org/archives/2018/07/27/8.htm
27 Jul 2018
In C difficile infection, adding IV bezlotoxumab to standard antibiotics reduced recurrence at 12 weeks
A commentary in ACP Journal Club noted that it would be reasonable to consider fidaxomicin or bezlotoxumab in patients at high risk for recurrent Clostridium difficile infection or in those for whom recurrence could have devastating consequences.
https://gastroenterology.acponline.org/archives/2017/05/26/10.htm
26 May 2017
ACG updates clinical guidelines on prevention, diagnosis, treatment of C. difficile infection
While the American College of Gastroenterology (ACG) included new recommendations for using fecal microbiota transplantation in recurrent Clostridioides difficile infection, it recommended against the use of probiotics for both primary and secondary prevention.
https://gastroenterology.acponline.org/archives/2021/05/28/1.htm
28 May 2021